IIDEFAR - INSTITUTO DE INVESTIGACIONES PARA EL DESCUBRIMIENTO DE FÁRMACOS DE ROSARIO: Últimas incorporaciones

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Evento Caracterización de metabolitos antifungicos producidos por bacillus atrophaeus

Garay Romero, Leticia Raquel; Garro, Hugo Alejandro ; Villegas, Liliana Beatriz ; Delfini, Claudio Daniel (Tech Science Press, 2021)
Artículo Metal coordination and peripheral substitution modulate the activity of cyclic tetrapyrroles on αS aggregation: a structural and cell-based study

González, Nazareno ; Gentile, Iñaki; Garro, Hugo Alejandro ; Delgado Ocaña, Susana ; Ramunno, Carla F.; Buratti, Fiamma Ayelen ; Griesinger, Christian; Fernandez, Claudio Oscar (Springer, 2019-12)
Artículo Structural heterogeneity of α-synuclein fibrils amplified from patient brain extracts

Strohäker, Timo; Jung, Byung Chul; Liou, Shu Hao; Fernandez, Claudio Oscar ; Riedel, Dietmar; Becker, Stefan; Halliday, Glenda M.; Bennati, Marina; Kim, Woojin S.; Lee, Seung Jae; Zweckstetter, Markus (Nature, 2019-12)
Artículo Vagal afferents contribute to sympathoexcitation-driven metabolic dysfunctions

Lorenzo Martín, L. Francisco; Menacho Márquez, Mauricio Ariel ; Fabbiano, Salvatore; Al Massadi, Omar; Abad, Antonio; Rodríguez Fdez, Sonia; Sevilla, María A.; Montero, María J.; Diéguez, Carlos; Nogueiras, Rubén; Bustelo, Xosé R. (BioScientifica, 2019-03)
Artículo Disruption of zinc and copper interactions with Ab(1–40) by a non-toxic, isoniazid-derived, hydrazone: a novel biometal homeostasis restoring agent in Alzheimer’s disease therapy?

Hauser Davis, R.A.; De Freitas, L. V.; Cukierman, D. S.; Cruz, W. S.; Miotto, Marco César ; Fernandez, Claudio Oscar ; Valiente Gabioud, Ariel Alejandro ; Fernández, C. O.; Rey, N. A. (Royal Society of Chemistry, 2015-04)
Artículo New Fluorinated Tyrosinase Inhibitor from a Chemically Engineered Essential Oil

García, Paula ; Salazar, Mario Oscar ; Ramallo, Ivana Ayelen ; Furlan, Ricardo Luis Eugenio (American Chemical Society, 2016-05)
Artículo Modern Strategies in Cancer Study: Drug Repositioning in Colorectal Cancer Treatment

Anselmino Dieterle, Luciano Emanuel ; Malizia, Florencia ; Menacho Márquez, Mauricio Ariel (Crimson Publisher, 2019-05)
Artículo Isoprenylcysteine carboxy methyltransferase (ICMT) is associated with tumor aggressiveness and its expression is controlled by the p53 tumor suppressor

Borini Etichetti, Carla Maria ; Di Benedetto, Carolina ; Rossi, Carolina; Baglioni, María Virginia ; Bicciato, Silvio; Del Sal, Giannino; Menacho Márquez, Mauricio Ariel ; Girardini Brovelli, Javier Enrique (American Society for Biochemistry and Molecular Biology, 2019-03)
Artículo Binucleating Hydrazonic Ligands and Their μ-Hydroxodicopper(II) Complexes as Promising Structural Motifs for Enhanced Antitumor Activity

Rada, Jesica Paola; Bastos, Beatriz S. M.; Anselmino Dieterle, Luciano Emanuel ; Franco, Chris H. J.; Lanznaster, Mauricio; Diniz, Renata; Fernandez, Claudio Oscar ; Menacho Márquez, Mauricio Ariel ; Percebom, Ana Maria; Rey, Nicolás A. (American Chemical Society, 2019-07)
Artículo Verbascoside, synthetic derivatives and other glycosides from Argentinian native plant species as potential antitumoral agents

Garro, Hugo Alejandro ; Bruna Haupt, Ezequiel Fabricio ; Cianchino, Valeria Andrea; Malizia, Florencia ; Favier, Silvina; Menacho Márquez, Mauricio Ariel ; Cifuente, Diego Alberto ; Fernandez, Claudio Oscar ; Pungitore, Carlos Rodolfo (Taylor & Francis Ltd, 2020-01)
Artículo Computational and in vitro Pharmacodynamics Characterization of 1A-116 Rac1 Inhibitor: Relevance of Trp56 in Its Biological Activity

González, Nazareno ; Cardama, Georgina Alexandra ; Chinestrad, Patricio Manuel; Robles Valero, Javier; Rodríguez Fdez, Sonia; Lorenzo Martín, L. Francisco; Bustelo, Xosé R.; Lorenzano Menna, Pablo ; Gomez, Daniel Eduardo (Frontiers Media, 2020-04-15)
Artículo Identification of a CIP4 PKA phosphorylation site involved in the regulation of cancer cell invasiveness and metastasis

Tonucci, Facundo Mauro ; Almada, Evangelina ; Borini Etichetti, Carla Maria ; Pariani, Alejandro Pedro ; Hidalgo, Florencia ; Rico, Maria Jose ; Girardini Brovelli, Javier Enrique ; Favre, Cristian ; Goldenring, James R.; Menacho Márquez, Mauricio Ariel ; Larocca, Maria Cecilia (Elsevier Ireland, 2019-10)
Artículo Rewiring Chemical Networks Based on Dynamic Dithioacetal and Disulfide Bonds

Orrillo, Alfredo Gastón ; la Venia, Agustina ; Escalante, Andrea Marta ; Furlan, Ricardo Luis Eugenio (Wiley VCH Verlag, 2018-03-23)
Artículo A Bioactive Trypanosoma cruzi Bromodomain Inhibitor from Chemically Engineered Extracts

Ramallo, Ivana Ayelen ; Alonso, Victoria Lucia ; Rúa, Federico ; Serra, Esteban Carlos ; Furlan, Ricardo Luis Eugenio (American Chemical Society, 2018-04)
Artículo Binding Modes of Phthalocyanines to Amyloid β Peptide and Their Effects on Amyloid Fibril Formation

Valiente Gabioud, Ariel Alejandro ; Riedel, Dietmar; Outeiro, Tiago F.; Menacho Márquez, Mauricio Ariel ; Griesinger, Christian; Fernandez, Claudio Oscar (Cell Press, 2018-03)
Artículo Membrane binding, internalization, and sorting of alpha-synuclein in the cell

Masaracchia, Caterina; Hnida, Marilena; Gerhardt, Ellen; Lopes da Fonseca, Tomás; Villar Pique, Anna; Branco, Tiago; Stahlberg, Markus A.; Dean, Camin; Fernandez, Claudio Oscar ; Milosevic, Ira; Outeiro, Tiago F. (NLM (Medline), 2018-08)
Artículo Aroylhydrazones constitute a promising class of ‘metal-protein attenuating compounds’ for the treatment of Alzheimer’s disease: a proof-of-concept based on the study of the interactions between zinc(II) and pyridine-2-carboxaldehyde isonicotinoyl hydrazone

Cukierman, Daphne S.; Accardo, Elio; Gomes, Rosana Garrido; De Falco, Anna; Miotto, Marco César ; Freitas, Maria Clara Ramalho; Lanznaster, Mauricio; Fernandez, Claudio Oscar ; Rey, Nicolás A. (Springer, 2018-12)
Artículo Neuroprotective alpha-cleavage of the human prion protein significantly impacts Cu(II) coordination at its His111 site

Sánchez López, Carolina; Fernandez, Claudio Oscar ; Quintanar, Liliana (Royal Society of Chemistry, 2018-01)
Artículo Interaction of Cu(i) with the Met-X3-Met motif of alpha-synuclein: binding ligands, affinity and structural features

Gentile, Iñaki; Garro, Hugo Alejandro ; Delgado Ocaña, Susana ; González, Nazareno ; Strohäker, Timo; Schibich, Daniela ; Quintanar, Liliana; Sambrotta, Luis Jorge ; Zweckstetter, Markus; Griesinger, Christian; Menacho Márquez, Mauricio Ariel ; Fernandez, Claudio Oscar (Royal Society of Chemistry, 2018-10)
Artículo Repositioning of Anti-parasitic Drugs in Cyclodextrin Inclusion Complexes for Treatment of Triple-Negative Breast Cancer

Priotti, Josefina ; Baglioni, María Virginia ; García, Agustina ; Rico, Maria Jose ; Leonardi, Darío ; Lamas, Maria Celina ; Menacho Márquez, Mauricio Ariel (Springer, 2018-11)

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