ESTEBAN CARLOS SERRA

Datos académicos

Lugar de trabajo	CONSEJO NACIONAL DE INVESTIGACIONES CIENTIFICAS Y TECNICAS / CENTRO CIENTIFICO TECNOLOGICO CONICET - ROSARIO / INSTITUTO DE BIOLOGIA MOLECULAR Y CELULAR DE ROSARIO \| UNIVERSIDAD NACIONAL DE ROSARIO / FACULTAD DE CS.BIOQUIMICAS Y FARMACEUTICAS / INSTITUTO DE BIOLOGIA MOLECULAR Y CELULAR DE ROSARIO
Título	Diplôme d?Habilitation à Diriger des Recherches\| Doctor de la Universidad Nacional de Rosario
Grado	Universitario de posgrado/doctorado
Campo de aplicación	Enf.Endemicas-Mal de Chagas
Especialidad	PARASITOLOGIA - BIOQUIMICA - MICROBIOLOGIA

PRODUCCION CIENTÍFICO TECNOLÓGICA

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Artículo 1,3,4-oxadiazoles as inhibitors of the atypical member of the BET family bromodomain factor 3 from Trypanosoma cruzi (TcBDF3)

Alonso, Victoria Lucia ; Escalante, Andrea Marta ; Rodríguez Araya, Elvio ; Frattini, Gianfranco ; Tavernelli, Luis Emilio ; Moreno, Diego Martin ; Furlan, Ricardo Luis Eugenio ; Serra, Esteban Carlos (Frontiers Media, 2024-10)
Artículo A Bioactive Trypanosoma cruzi Bromodomain Inhibitor from Chemically Engineered Extracts

Ramallo, Ivana Ayelen ; Alonso, Victoria Lucia ; Rúa, Federico ; Serra, Esteban Carlos ; Furlan, Ricardo Luis Eugenio (American Chemical Society, 2018-04)
Artículo Aim for the readers! Bromodomains as new targets against Chagas` disease

Alonso, Victoria Lucia ; Tavernelli, Luis Emilio ; Pezza, Alejandro ; Cribb, Pamela ; Ritagliati, Carla ; Serra, Esteban Carlos (Bentham Science Publishers, 2018-10)
Artículo Alpha-Tubulin Acetylation in Trypanosoma cruzi: A Dynamic Instability of Microtubules Is Required for Replication and Cell Cycle Progression

Alonso, Victoria Lucia ; Carloni, Mara Emilia; Silva Goncalves, Camila; Martinez Peralta, Gonzalo ; Chesta, María Eugenia ; Pezza, Alejandro ; Tavernelli, Luis Emilio ; Motta, Maria Cristina M.; Serra, Esteban Carlos (Frontiers Media, 2021-03)
Artículo Antitrypanosomal and antileishmanial activity of prenyl-1,2,3-triazoles

Porta, Exequiel Oscar Jesús ; Jäger, Sebastián N.; Nocito, Isabel; Lepesheva, Galina I.; Serra, Esteban Carlos ; Tekwani, Babu L.; Labadie, Guillermo Roberto (Royal Society of Chemistry, 2017-03)
Artículo Construction of three new Gateway® expression plasmids for Trypanosoma cruzi

Alonso, Victoria Lucia ; Ritagliati, Carla ; Cribb, Pamela ; Serra, Esteban Carlos (Fundacao Oswaldo Cruz, 2014-12)
Datos de investigación Data generated from the simulation of the structures of the CRL4 E3 ligase from Homo sapiens and their homolgs of Trypanosoma cruzi, Trypanosoma brucei and Leishmania major using MultimerMapper

Serra, Esteban Carlos Rodríguez Araya, Elvio (2025)
Artículo Deciphering Divergent Trypanosomatid Nuclear Complexes by Analyzing Interactomic Datasets with AlphaFold2 and Genetic Approaches

Rodríguez Araya, Elvio ; Merli, Marcelo Luciano ; Cribb, Pamela ; de Souza, Vinicius C.; Serra, Esteban Carlos (American Chemical Society, 2023-05)
Artículo Deficient control of Trypanosoma cruzi infection in C57BL/6 mice is related to a delayed specific IgG response and increased macrophage production of pro-inflammatory cytokines

Perez, Ana Rosa ; Tamae Kakazu, M.; Pascutti, María Fernanda ; Roggero, Eduardo Angel; Serra, Esteban Carlos ; Revelli, Silvia Susana; Bottasso, Oscar Adelmo (Pergamon-Elsevier Science Ltd, 2005-09)
Artículo Development and in vitro/in vivo evaluation of a novel benznidazole liquid dosage form using a quality-by-design approach

Santos Souza, Higo Fernando; Real, Daniel Andres ; Leonardi, Darío ; Rocha, Sandra Carla; Alonso, Victoria Lucia ; Serra, Esteban Carlos ; Silber, Ariel Mariano; Salomon, Claudio Javier (Wiley Blackwell Publishing, Inc, 2017-12)
Artículo Differential susceptibility to acute Trypanosoma cruzi infection in BALB/c and C57BL/6 mice is not associated with a distinct parasite load but cytokine abnormalities

Roggero, Eduardo Angel; Perez, Ana Rosa ; Tamae Kakazu, M.; Piazzon, Margarita Isabel ; Nepomnaschy, Irene ; Wietzerbin, J.; Serra, Esteban Carlos ; Revelli, Silvia Susana; Bottasso, Oscar Adelmo (Wiley Blackwell Publishing, Inc, 2002-12)
Artículo Discovery of a Biologically Active Bromodomain Inhibitor by Target-Directed Dynamic Combinatorial Chemistry

García, Paula; Alonso, Victoria Lucia ; Serra, Esteban Carlos ; Escalante, Andrea Marta ; Furlan, Ricardo Luis Eugenio (American Chemical Society, 2018-10)
Artículo DNA lesions that block transcription induce the death of Trypanosoma cruzi via ATR activation, which is dependent on the presence of R-loops

Mendes, Isabela Cecilia; dos Reis Bertoldo, Willian; Miranda-Junior, Adalberto Sales; Assis, Antônio Vinícius de; Repolês, Bruno Marçal; Ferreira, Wesley Roger Rodrigues; Chame, Daniela Ferreira; Souza, Daniela De Laet; Pavani, Raphael Souza; Macedo, Andrea Mara; Franco, Glória Regina; Serra, Esteban Carlos ; Perdomo, Virginia ; Menck, Carlos Frederico Martins; da Silva Leandro, Giovana; Fragoso, Stenio Perdigão; Barbosa Elias, Maria Carolina Quartim; Machado, Carlos Renato (Elsevier Science, 2024-09)
Artículo Efficacy of novel benznidazole solutions during the experimental infection with Trypanosoma cruzi

Manarin, Romina ; Lamas, Maria Celina ; Bottasso, Emanuel; Serra, Esteban Carlos ; Revelli, Silvia Susana; Salomon, Claudio Javier (Elsevier Ireland, 2013-02)
Artículo Essential Bromodomain TcBDF2 as a Drug Target against Chagas Disease

Pezza, Alejandro ; Tavernelli, Luis Emilio ; Alonso, Victoria Lucia ; Perdomo, Virginia ; Gabarro, Raquel; Prinjha, Rab; Rodríguez Araya, Elvio ; Rioja, Inmaculada; Docampo, Roberto; Calderón, Felix; Martin, Julio; Serra, Esteban Carlos (American Chemical Society, 2022-04)
Artículo Glycosomal bromodomain factor 1 from Trypanosoma cruzi enhances trypomastigote cell infection and intracellular amastigote growth

Ritagliati, Carla ; Villanova, Gabriela Vanina ; Alonso, Victoria Lucia ; Araujo Zuma, Aline; Cribb, Pamela ; Motta, Maria Cristina Machado; Serra, Esteban Carlos (Portland Press, 2015-12)
Evento Hit Optimization Of A Trypanosoma Cruzi Bromodomain Inhibitor Identified Using Combinatorial Chemistry

Alonso, Victoria Lucia ; Escalante, Andrea Marta ; Furlan, Ricardo Luis Eugenio ; Serra, Esteban Carlos (Fundación Revista Medicina, 2019)
Artículo Identification of novel bromodomain inhibitors of Trypanosoma cruzi bromodomain factor 2 ( Tc BDF2) using a fluorescence polarization-based high-throughput assay

Tavernelli, Luis Emilio ; Alonso, Victoria Lucia ; Peña, Imanol; Rodríguez Araya, Elvio ; Manarin, Romina ; Cantizani, Juan; Martin, Julio; Salamanca, Juan; Bamborough, Paul; Calderón, Felix; Gabarro, Raquel; Serra, Esteban Carlos (American Society for Microbiology, 2024-08)
Artículo Lysine Acetylation: Elucidating the Components of an Emerging Global Signaling Pathway in Trypanosomes

Alonso, Victoria Lucia ; Serra, Esteban Carlos (Hindawi Publishing Corporation, 2012-10)
Artículo Overexpression of bromodomain factor 3 in Trypanosoma cruzi (TcBDF3) affects differentiation of the parasite and protects it against bromodomain inhibitors

Alonso, Victoria Lucia ; Ritagliati, Carla ; Cribb, Pamela ; Cricco, Julia Alejandra ; Serra, Esteban Carlos (Wiley Blackwell Publishing, Inc, 2016-06)

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