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  • Miniatura
    Item type: Artículo ,
    Ecotoxicological Impact of Agro‐Industry on Streams From a South American Basin: Amphibian Tadpoles as Indicators of Environmental Health
    (Water Environment Federation, 2025-06)
    Cuzziol Boccioni, Ana Paula
    ;
    Lajmanovich, Rafael Carlos
    ;
    Repetti, María Rosa
    ;
    Attademo, Andres Maximiliano
    ;
    Zalazar, Cristina Susana
    This study aimed to evaluate complex contamination due to anthropic activities related to urban, industrial and agricultural activities in four streams of Entre Ríos-Argentina(Las Conchas, LC; Espinillo, ES; Crespo, CR; Las Tunas, LT), being the first one the main water sources of subtropical riparian conservation reserve “Parque Escolar Rural Enrique Berduc” (PEREB). Physicochemical and bacteriological parameters and pesticide residues were studied on sediment and water samples. Toxicity bioassays on Rhinella arenarum tadpoles were performed to analyze ecotoxicological effects. Sediment from LC stream had the highest glyphosate concentration recorded in South American (5002 μg/kg). Bioassays showed lethality (100%) in undiluted CR and LT treatments. Sublethal effects included thyrotoxicosis, neurotoxicity, and genotoxicity on treated ES, CR, and LT tadpoles.These findings highlight the alarming environmental degradation threatening “One health,” emphasizing the need for sustainable practices and severe control by science and government to protect and ecological restore freshwater sources.
  • Miniatura
    Item type: Artículo ,
    The Toxicity of Microplastics Explorer (ToMEx) 2.0
    (Springer, 2025-09)
    Hampton, Leah M. Thornton
    ;
    Wyler, Dana Briggs
    ;
    Almroth, Bethanie Carney
    ;
    Coffin, Scott
    ;
    Cowger, Win
    In 2021 the Toxicity of Microplastics Explorer (ToMEx, https://microplastics.sccwrp.org) was released as an open source, open access database and web application for microplastics toxicity. Since then, it has been utilized by the microplastic research community for the exploration, visualization, and analysis of toxicity data for both hazard characterization and risk assessment. The peer-reviewed literature has continued to grow exponentially, making ToMEx out-of-date. To ensure the continued utility of ToMEx, an international crowd-sourcing approach was utilized to update ToMEx by extracting data from additional studies published since the original release. Through this process, both the aquatic and human health ToMEx databases roughly doubled in size, and modest increases in data diversity (e.g., number of species represented, types of test particles) were observed in the aquatic organisms database. However, most trends (e.g., greater toxicities observed with smaller particle sizes, lack of dose–response data etc.) observed in the first iteration of ToMEx remained constant. A previously developed framework for deriving ecological health-based microplastic thresholds using species sensitivity distributions was reapplied to determine how thresholds and their associated uncertainty intervals would change following the database update. Twelve new studies passed minimum screening criteria and were deemed fit for the purpose of threshold derivation. The addition of new data allowed for the separation of freshwater and marine compartments which had previously been combined due to a lack of applicable toxicity data for freshwater species. When molecular and cellular level endpoints were included, freshwater thresholds were comparable or increased from values calculated using previous data (-5 to 2.5-fold change) whereas marine thresholds dramatically decreased (-5000 to -29-fold change). However, when endpoints were restricted to organism and above, marine and freshwater thresholds were comparable to those calculated previously (-20 to 14-fold change). Confidence intervals for both marine and freshwater thresholds remained wide. The doubling of the database increases the value of ToMEx for researchers, particularly those focused on characterizing hazards associated with microplastics. Its utility remains limited for environmental managers as 89% of studies in ToMEx 2.0 failed to meet minimum screening criteria for threshold derivation, highlighting the need to generate fit-for-purpose toxicity data for threshold development. However, ToMEx continues to be a useful research tool, and future iterations could become even more powerful through novel artificial intelligence applications to streamline data curation and even predict toxicological outcomes.
  • Miniatura
    Item type: Capítulo de libro ,
    Agriculturas familiares en Chaco y Formosa frente a la retracción algodonera
    (Asociación Argentina de Sociología Rural, 2024)
    Martínez, Gerardo
    ;
    Machuca, Darío Agustín
    ;
    López Castro, Natalia Inés
    ;
    Gómez, César
    ;
    González Maraschio, María Fernanda
    Teniendo en cuenta las similitudes y diferencias entre Chaco y Formosa, este capítulo tiene por objetivo analizar las transformaciones transitadas por las agriculturas familiares en ambos distritos durante los últimos años. Si bien se pretende concentrar la mayor parte de la exposición en el período posterior a la publicación del libro original (López Castro y Prividera, 2011), el estudio de ciertos elementos implica recurrir en ciertos casos a periodicidades mayores. Por otro lado, dada una serie de elementos históricos, económicos y ambientales propios de la región chaqueña, las jurisdicciones en cuestión fueron seleccionadas por constituir ejemplos de diversas aristas propias del desarrollo del capitalismo en el sector agrario de áreas periféricas del complejo productivo argentino.
  • Miniatura
    Item type: Artículo ,
    Industria metalúrgica y acción sindical en el Conurbano Sur: Un desafío en tiempos de transformación
    (Univesidad Nacional Arturo Jauretche. Secretaría de Política y Territorio, 2025-06)
    Trujillo Salazar, Lucia Paola
    ;
    Barrera, Facundo
    ;
    Beliera, Anabel Angélica
    ;
    Morris, María Belén
    La metalurgia sigue siendo el corazón industrial del Conurbano Sur. En nuestro proyecto analizamos el quehacer sindical en grandes fábricas, medianas empresas y pequeños talleres, con realidades muy distintas pero unidas por la representación sindical de la UOM. Con datos estadísticos y voces de las delegadas y delegados en el territorio, buscamos comprender cómo se construyen mejores condiciones y derechos laborales, salarios, oportunidades de capacitación y bienestar, en un entramado donde el sindicato no solo negocia, también transforma la vida cotidiana.
  • Miniatura
    Item type: Artículo ,
    Corrigendum to “Nitro-Oleic acid protects from neovascularization, oxidative stress, gliosis and neurodegeneration in oxygen-induced retinopathy” [Redox Biol. 83 (2025) 103634]
    (Elsevier, 2025-09)
    Vaglienti, María Victoria
    ;
    Paz, Maria Constanza
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    Gutierrez, Maria Victoria
    ;
    Subirada Caldarone, Paula Virginia
    ;
    Luna, Jose
    Inflammation and oxidative stress are involved in Proliferative Retinopathies (PR). Müller glial cells (MGCs) and microglia play pivotal roles in pathological neovascularization (NV) and neurodegeneration in PR. Nitro-fatty acids are important electrophilic signaling mediators with anti-inflammatory and antioxidant properties. Herein, our goal was to evaluate the cytoprotective effect of nitro-oleic acid (NO2-OA) on neurons, MGCs and microglia in a mouse model of oxygen-induced retinopathy (OIR). NO2-OA induced vascular regrowth and reduced NV at P17 OIR, although no difference in the proangiogenic/antiangiogenic (VEGF-A/PEDF) balance was found between NO2-OA treatment and vehicle. In addition, Western blot and immunofluorescence assays showed that NO2-OA prevented gliosis at P17 OIR and decreased the number and activation of IBA1+ retinal myeloid cells. However, NO2-OA did not restore the decrease in expression of glutamine synthase (GS). Loss of retinal function in OIR mouse model measured by electroretinography was ameliorated, mainly at P26 OIR, after NO2-OA treatment. Western blot analysis of retinas from OIR mice revealed decreased levels of caspase-3 protein and increased number of TUNEL-positive cells at P26 compared to RA. Notably, these alterations were partially prevented after NO2-OA treatment. Besides, NO2-OA attenuates oxidative stress induced in MGCs exposed to aqueous humor from patients with different stages of PR. These findings highlight NO2-OA as a promising therapeutic strategy targeting both vascular and neuroglial components in PR, suggesting its potential clinical relevance.