Miotto, Marco César

PRODUCCION CIENTÍFICO TECNOLÓGICA

Mostrando ítems 1-10 de 10

Artículo A moderate metal-binding hydrazone meets the criteria for a bioinorganic approach towards Parkinson's disease: Therapeutic potential, blood-brain barrier crossing evaluation and preliminary toxicological studies

Cukierman, Daphne Schneider; Pinheiro, Ana Beatriz; Castiñeiras-Filho, Sergio L.P.; da Silva, Anastácia Sá P.; Miotto, Marco César ; De Falco, Anna; de P. Ribeiro, Thales; Maisonette, Silvia; da Cunha, Alessandra L.M.C.; Hauser-Davis, Rachel A.; Fernandez, Claudio Oscar ; Aucélio, Ricardo Q.; Outeiro, Tiago F.; Pereira, Marcos D.; Fernandez, Claudio Oscar ; Rey, Nicolás A. (Elsevier Science Inc, 2017-05)
Artículo Aroylhydrazones constitute a promising class of ‘metal-protein attenuating compounds’ for the treatment of Alzheimer’s disease: a proof-of-concept based on the study of the interactions between zinc(II) and pyridine-2-carboxaldehyde isonicotinoyl hydrazone

Cukierman, Daphne S.; Accardo, Elio; Gomes, Rosana Garrido; De Falco, Anna; Miotto, Marco César ; Freitas, Maria Clara Ramalho; Lanznaster, Mauricio; Fernandez, Claudio Oscar ; Rey, Nicolás A. (Springer, 2018-12)
Artículo Bioinorganic Chemistry of Parkinson's Disease: Affinity and Structural Features of Cu(I) Binding to the Full-Length β-Synuclein Protein

Miotto, Marco César ; Pavese, Mayra D.; Quintanar, Liliana; Zweckstetter, Markus; Griesinger, Christian; Fernandez, Claudio Oscar (American Chemical Society, 2017-09)
Artículo Bioinorganic chemistry of synucleinopathies: Deciphering the binding features of Met motifs and His-50 in AS-Cu(I) interactions

Miotto, Marco César ; Binolfi, Andrés ; Zweckstetter, Markus; Griesinger, Christian; Fernandez, Claudio Oscar (Elsevier Science Inc, 2014-12)
Artículo Copper Binding to the N‑Terminally Acetylated, Naturally Occurring Form of Alpha-Synuclein Induces Local Helical Folding

Miotto, Marco César ; Valiente Gabioud, Ariel Alejandro ; Rossetti, Giulia; Zweckstetter, Markus; Carloni, Paolo; Selenko, Philipp; Griesinger, Christian; Binolfi, Andrés ; Fernandez, Claudio Oscar (American Chemical Society, 2015-05)
Artículo Copper Coordination Features of Human Islet Amyloid Polypeptide: The Type 2 Diabetes Peptide

Sánchez López, Carolina; Cortés Mejía, Rodrigo; Miotto, Marco César ; Binolfi, Andrés ; Fernandez, Claudio Oscar ; Del Campo, Jorge M.; Quintanar, Liliana (American Chemical Society, 2016-10)
Artículo Disruption of zinc and copper interactions with Ab(1–40) by a non-toxic, isoniazid-derived, hydrazone: a novel biometal homeostasis restoring agent in Alzheimer’s disease therapy?

Hauser Davis, R.A.; De Freitas, L. V.; Cukierman, D. S.; Cruz, W. S.; Miotto, Marco César ; Fernandez, Claudio Oscar ; Valiente Gabioud, Ariel Alejandro ; Fernández, C. O.; Rey, N. A. (Royal Society of Chemistry, 2015-04)
Artículo Phthalocyanines as Molecular Scaffolds to Block Disease-Associated Protein Aggregation

Valiente Gabioud, Ariel Alejandro ; Miotto, Marco César ; Chesta, María Eugenia ; Lombardo, Veronica Andrea ; Binolfi, Andrés ; Fernandez, Claudio Oscar (American Chemical Society, 2016-05)
Artículo Site-Specific Copper-Catalyzed Oxidation of α-Synuclein: Tightening the Link between Metal Binding and Protein Oxidative Damage in Parkinson’s Disease

Miotto, Marco César ; Rodriguez, Esaú E; Valiente Gabioud, Ariel Alejandro ; Torres Monserrat, Valentina; Binolfi, Andrés ; Quintanar, Liliana; Zweckstetter, Markus; Griesinger, Christian; Fernandez, Claudio Oscar (American Chemical Society, 2014-04)
Artículo Spectroscopic and Theoretical Study of CuI Binding to His111 in the Human Prion Protein Fragment 106-115

Arcos López, Trinidad; Qayyum, Munzarin; Rivillas Acevedo, Lina; Miotto, Marco César ; Grande Aztatzi, Rafael; Fernandez, Claudio Oscar ; Hedman, Britt; Hodgson, Keith O.; Vela, Alberto; Solomon, Edward I.; Quintanar, Liliana (American Chemical Society, 2016-03)

Mostrando ítems 1-10 de 10