CLAUDIO OSCAR FERNANDEZ

Datos académicos

Lugar de trabajo	UNIVERSIDAD NACIONAL DE ROSARIO / CENTRO DE ESTUDIOS INTERDISCIPLINARIOS
Título	Doctor de la Universidad de Buenos Aires
Grado	Universitario de posgrado/doctorado
Campo de aplicación	Prom.Gral.del Conoc.-Cs.Exactas y Naturales
Especialidad	BIOQUIMICA

PRODUCCION CIENTÍFICO TECNOLÓGICA

Mostrando ítems 1-20 de 30

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Artículo A moderate metal-binding hydrazone meets the criteria for a bioinorganic approach towards Parkinson's disease: Therapeutic potential, blood-brain barrier crossing evaluation and preliminary toxicological studies

Cukierman, Daphne Schneider; Pinheiro, Ana Beatriz; Castiñeiras-Filho, Sergio L.P.; da Silva, Anastácia Sá P.; Miotto, Marco César ; De Falco, Anna; de P. Ribeiro, Thales; Maisonette, Silvia; da Cunha, Alessandra L.M.C.; Hauser-Davis, Rachel A.; Fernandez, Claudio Oscar ; Aucélio, Ricardo Q.; Outeiro, Tiago F.; Pereira, Marcos D.; Fernandez, Claudio Oscar ; Rey, Nicolás A. (Elsevier Science Inc, 2017-05)
Artículo Aromaticity at position 39 in α-synuclein: A modulator of amyloid fibril assembly and membrane-bound conformations

Buratti, Fiamma Ayelen ; Boeffinger, Nicola; Garro, Hugo Alejandro ; Flores, Jesica Soledad; Hita, Francisco Javier ; Do Carmo Goncalves, Phelippe ; Dos Reis Copello, Federico ; Lizarraga, Leonardo ; Rossetti, Giulia; Carloni, Paolo; Zweckstetter, Markus; Outeiro, Tiago F.; Eimer, Stefan; Griesinger, Christian; Fernandez, Claudio Oscar (John Wiley & Sons, 2022-07)
Artículo Aroylhydrazones constitute a promising class of ‘metal-protein attenuating compounds’ for the treatment of Alzheimer’s disease: a proof-of-concept based on the study of the interactions between zinc(II) and pyridine-2-carboxaldehyde isonicotinoyl hydrazone

Cukierman, Daphne S.; Accardo, Elio; Gomes, Rosana Garrido; De Falco, Anna; Miotto, Marco César ; Freitas, Maria Clara Ramalho; Lanznaster, Mauricio; Fernandez, Claudio Oscar ; Rey, Nicolás A. (Springer, 2018-12)
Artículo Binding Modes of Phthalocyanines to Amyloid β Peptide and Their Effects on Amyloid Fibril Formation

Valiente Gabioud, Ariel Alejandro ; Riedel, Dietmar; Outeiro, Tiago F.; Menacho Márquez, Mauricio Ariel ; Griesinger, Christian; Fernandez, Claudio Oscar (Cell Press, 2018-03)
Artículo Binucleating Hydrazonic Ligands and Their μ-Hydroxodicopper(II) Complexes as Promising Structural Motifs for Enhanced Antitumor Activity

Rada, Jesica Paola; Bastos, Beatriz S. M.; Anselmino Dieterle, Luciano Emanuel ; Franco, Chris H. J.; Lanznaster, Mauricio; Diniz, Renata; Fernandez, Claudio Oscar ; Menacho Márquez, Mauricio Ariel ; Percebom, Ana Maria; Rey, Nicolás A. (American Chemical Society, 2019-07)
Artículo Bioinorganic Chemistry of Parkinson's Disease: Affinity and Structural Features of Cu(I) Binding to the Full-Length β-Synuclein Protein

Miotto, Marco César ; Pavese, Mayra D.; Quintanar, Liliana; Zweckstetter, Markus; Griesinger, Christian; Fernandez, Claudio Oscar (American Chemical Society, 2017-09)
Artículo Bioinorganic chemistry of synucleinopathies: Deciphering the binding features of Met motifs and His-50 in AS-Cu(I) interactions

Miotto, Marco César ; Binolfi, Andrés ; Zweckstetter, Markus; Griesinger, Christian; Fernandez, Claudio Oscar (Elsevier Science Inc, 2014-12)
Artículo Conformational ensemble of human α-synuclein physiological form predicted by molecular simulations

Rossetti, German ; Musiani, F.; Abad, E.; Dibenedetto, D.; Mouhib, H.; Fernandez, Claudio Oscar ; Carloni, P. (Royal Society of Chemistry, 2016-01)
Artículo Copper Binding to the N‑Terminally Acetylated, Naturally Occurring Form of Alpha-Synuclein Induces Local Helical Folding

Miotto, Marco César ; Valiente Gabioud, Ariel Alejandro ; Rossetti, Giulia; Zweckstetter, Markus; Carloni, Paolo; Selenko, Philipp; Griesinger, Christian; Binolfi, Andrés ; Fernandez, Claudio Oscar (American Chemical Society, 2015-05)
Artículo Copper Coordination Features of Human Islet Amyloid Polypeptide: The Type 2 Diabetes Peptide

Sánchez López, Carolina; Cortés Mejía, Rodrigo; Miotto, Marco César ; Binolfi, Andrés ; Fernandez, Claudio Oscar ; Del Campo, Jorge M.; Quintanar, Liliana (American Chemical Society, 2016-10)
Artículo Copper(II) and the pathological H50Q α-synuclein mutant: Environment meets genetics

Villar Piqué, Anna; Rossetti, Giulia; Ventura, Salvador; Carloni, Paolo; Fernandez, Claudio Oscar ; Outeiro, Tiago Fleming (Taylor and Francis Inc., 2017-01)
Artículo Disruption of zinc and copper interactions with Ab(1–40) by a non-toxic, isoniazid-derived, hydrazone: a novel biometal homeostasis restoring agent in Alzheimer’s disease therapy?

Hauser Davis, R.A.; De Freitas, L. V.; Cukierman, D. S.; Cruz, W. S.; Miotto, Marco César ; Fernandez, Claudio Oscar ; Valiente Gabioud, Ariel Alejandro ; Fernández, C. O.; Rey, N. A. (Royal Society of Chemistry, 2015-04)
Artículo Effects of alpha-synuclein post-translational modifications on metal binding

González, Nazareno ; Arcos López, Trinidad; König, Annekatrin; Quintanar, Liliana; Menacho Márquez, Mauricio Ariel ; Outeiro, Tiago F.; Fernandez, Claudio Oscar (Wiley Blackwell Publishing, Inc, 2019-05-16)
Artículo Environmental and genetic factors support the dissociation between α-synuclein aggregation and toxicity

Villar Piqué, Anna; Da Fonseca, Tomás Lopes; Sant'Anna, Ricardo; Szegö, Éva Mónika; Fonseca Ornelas, Luis; Pinho, Raquel; Carija, Anita; Gerhardt, Ellen; Masaracchia, Caterina; Gonzalez, Enrique Abad; Rossetti, Giulia; Carloni, Paolo; Fernandez, Claudio Oscar ; Foguel, Debora; Milosevic, Ira; Zweckstetter, Markus; Ventura, Salvador; Outeiro, Tiago Fleming (National Academy of Sciences, 2016-10)
Artículo Interaction of Cu(i) with the Met-X3-Met motif of alpha-synuclein: binding ligands, affinity and structural features

Gentile, Iñaki; Garro, Hugo Alejandro ; Delgado Ocaña, Susana ; González, Nazareno ; Strohäker, Timo; Schibich, Daniela ; Quintanar, Liliana; Sambrotta, Luis Jorge ; Zweckstetter, Markus; Griesinger, Christian; Menacho Márquez, Mauricio Ariel ; Fernandez, Claudio Oscar (Royal Society of Chemistry, 2018-10)
Artículo Long-Range Correlated Dynamics in Intrinsically Disordered Proteins

Parigi, Giacomo ; Rezaei Ghaleh, Nasrollah ; Giachetti, Andrea; Becker, Stefan ; Fernandez, Claudio Oscar ; Blackledger, Martin; Griesinger, Christian; Zweckstetter, Markus; Luchinat, Claudio (American Chemical Society, 2014-10)
Artículo Membrane binding, internalization, and sorting of alpha-synuclein in the cell

Masaracchia, Caterina; Hnida, Marilena; Gerhardt, Ellen; Lopes da Fonseca, Tomás; Villar Pique, Anna; Branco, Tiago; Stahlberg, Markus A.; Dean, Camin; Fernandez, Claudio Oscar ; Milosevic, Ira; Outeiro, Tiago F. (NLM (Medline), 2018-08)
Artículo Metal coordination and peripheral substitution modulate the activity of cyclic tetrapyrroles on αS aggregation: a structural and cell-based study

González, Nazareno ; Gentile, Iñaki; Garro, Hugo Alejandro ; Delgado Ocaña, Susana ; Ramunno, Carla F.; Buratti, Fiamma Ayelen ; Griesinger, Christian; Fernandez, Claudio Oscar (Springer, 2019-12)
Artículo Neuroprotective alpha-cleavage of the human prion protein significantly impacts Cu(II) coordination at its His111 site

Sánchez López, Carolina; Fernandez, Claudio Oscar ; Quintanar, Liliana (Royal Society of Chemistry, 2018-01)
Artículo Phthalocyanines as Molecular Scaffolds to Block Disease-Associated Protein Aggregation

Valiente Gabioud, Ariel Alejandro ; Miotto, Marco César ; Chesta, María Eugenia ; Lombardo, Veronica Andrea ; Binolfi, Andrés ; Fernandez, Claudio Oscar (American Chemical Society, 2016-05)

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