LEONARDO EZEQUIEL RIAFRECHA

Datos académicos

Lugar de trabajo	UNIVERSIDAD NACIONAL DE LA PLATA / FACULTAD DE CS.EXACTAS / DEPARTAMENTO DE QUIMICA
Título	Doctor de la Facultad de Ciencias Exactas
Grado	Universitario de posgrado/doctorado
Campo de aplicación	Qca.,Petroqca.y Carboqca.-Ind.Farmaceutica
Especialidad	Cálculo computacional y síntesis de carbohidratos

PRODUCCION CIENTÍFICO TECNOLÓGICA

Mostrando ítems 1-15 de 15

Artículo Anti-tubercular and antioxidant activities of C-glycosyl carbonic anhydrase inhibitors: towards the development of novel chemotherapeutic agents against Mycobacterium tuberculosis

Zaro, Maria Jose ; Bortolotti, Ana ; Riafrecha, Leonardo Ezequiel ; Concellón, Analía ; Morbidoni, Héctor Ricardo; Colinas, Pedro Alfonso (Taylor & Francis Ltd, 2016-05)
Artículo Attachment of carbohydrates to methoxyaryl moieties leads to highly selective inhibitors of the cancer associated carbonic anhydrase isoforms IX and XII

Riafrecha, Leonardo Ezequiel ; Rodríguez, Oscar Mariano; Vullo, Daniela; Supuran, Claudiu T.; Colinas, Pedro Alfonso (Pergamon-Elsevier Science Ltd., 2014-08)
Artículo C-cinnamoyl glycosides: An emerging “Tail” for the development of selective carbonic anhydrase inhibitors

Martínez, Helberth Llantén; Riafrecha, Leonardo Ezequiel ; Colinas, Pedro Alfonso (Bentham Science Publishers, 2019-07)
Artículo C-glycosides incorporating the 6-methoxy-2-naphthyl moiety are selective inhibitors of fungal and bacterial carbonic anhydrases

Riafrecha, Leonardo Ezequiel ; Vullo, Daniela; Supuran, Claudiu T.; Colinas, Pedro Alfonso (Taylor & Francis, 2015-09)
Artículo Glucoimines incorporating classical and non-classical carbonic anhydrase pharmacophores: Design, synthesis, conformational analysis, biological evaluation, and docking simulations

Vasquez, Ivana Raquel ; Riafrecha, Leonardo Ezequiel ; Martinez Heredia, Leandro ; Echeverría, Gustavo Alberto ; Piro, Oscar Enrique ; Lavecchia, Martín José ; Supuran, Claudiu T.; Colinas, Pedro Alfonso (Elsevier Science, 2024-08)
Artículo Glycosyl Isoxazoles for Targeting of Tumor Microenvironment and Cancer Cells: Highly Selective Inhibitors of Carbonic Anhydrases IX and XII Showing Cytotoxic Activity

Le Pors, Macarena Soledad ; Santa Maria de la Parra, Lucía ; Riafrecha, Leonardo Ezequiel ; Vullo, Daniela; Leon, Ignacio Esteban ; Supuran, Claudiu T.; Colinas, Pedro Alfonso (John Wiley & Sons, 2023-03)
Artículo Green Biphasic Synthesis, X-Ray Diffraction Structure and Conformational Analysis of O-Glycosylmethyl Isoxazoles: Potential Substrates of GLUT-1 Glucose Transporter

Le Pors, Macarena Soledad ; Barri, Ivan Alejandro ; Riafrecha, Leonardo Ezequiel ; Echeverría, Gustavo Alberto ; Piro, Oscar Enrique ; Colinas, Pedro Alfonso (John Wiley & Sons, 2022-01)
Artículo Improving the carbonic anhydrase inhibition profile of the sulfamoylphenyl pharmacophore by attachment of carbohydrate moieties

Riafrecha, Leonardo Ezequiel ; Bua, Silvia; Supuran, Claudiu T.; Colinas, Pedro Alfonso (Academic Press Inc Elsevier Science, 2018-02)
Artículo Inhibition of the β-carbonic anhydrases from Mycobacterium tuberculosis with C-cinnamoyl glycosides: Identification of the first inhibitor with anti-mycobacterial activity

Buchieri, María Virginia ; Riafrecha, Leonardo Ezequiel ; Rodríguez, Oscar Mariano; Vullo, Daniela; Morbidoni, Héctor Ricardo; Supuran, Claudiu T.; Colinas, Pedro Alfonso (Pergamon-Elsevier Science Ltd., 2013-01)
Artículo Inhibition of β-carbonic anhydrases from Brucella suis with C-cinnamoyl glycosides incorporating the phenol moiety

Riafrecha, Leonardo Ezequiel ; Vullo, Daniela; Ouahrani Bettache, Safia; Köhler, Stephan; Dumy, Pascal; Winum, Jean Yves; Supuran, Claudiu T.; Colinas, Pedro Alfonso (Taylor & Francis Ltd, 2015-11)
Tesis Síntesis de glicomiméticos inhibidores de anhidrasas carbónicas como potenciales agentes antitumorales y antibacterianos

Riafrecha, Leonardo Ezequiel (2017-12-18) Director: Colinas, Pedro Alfonso
Artículo Spontaneous resolution of diastereomeric glycosyl isoxazolines: a combined theoretical and experimental study in solution and in the crystalline form.

Barri, Ivan Alejandro ; Riafrecha, Leonardo Ezequiel ; Echeverría, Gustavo Alberto ; Piro, Oscar Enrique ; Colinas, Pedro Alfonso (Elsevier Science, 2024-04)
Artículo Synthesis and carbonic anhydrase inhibitory effects of new N-glycosylsulfonamides incorporating the phenol moiety

Riafrecha, Leonardo Ezequiel ; Bua, Silvia; Supuran, Claudiu T.; Colinas, Pedro Alfonso (Pergamon-Elsevier Science Ltd, 2016-07)
Artículo Synthesis of C-cinnamoyl glycosides and their inhibitory activity against mammalian carbonic anhydrases

Riafrecha, Leonardo Ezequiel ; Rodríguez, Oscar Mariano; Vullo, Daniela; Supuran, Claudiu T.; Colinas, Pedro Alfonso (Elsevier, 2012-09)
Artículo Vanillin enones as selective inhibitors of the cancer associated carbonic anhydrase isoforms IX and XII: The out of the active site pocket for the design of selective inhibitors?

Riafrecha, Leonardo Ezequiel ; Le Pors, Macarena Soledad ; Lavecchia, Martín José ; Bua, Silvia; Supuran, Claudiu T.; Colinas, Pedro Alfonso (Taylor & Francis Ltd, 2021-10-04)

Mostrando ítems 1-15 de 15