Artículo
C-cinnamoyl glycosides: An emerging “Tail” for the development of selective carbonic anhydrase inhibitors
Fecha de publicación:
07/2019
Editorial:
Bentham Science Publishers
Revista:
Current Medicinal Chemistry
ISSN:
0929-8673
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
Attachment of different tails to the well-known carbonic anhydrase (CA) pharma-cophores has led to the development of several new CA inhibitors (CAIs). A very good example of such “tails” is constituted by carbohydrates, which represent a wide range of chemo-types, leading thus to a high number of new CAIs. In the last years, several C-cinnamoyl glycosides containing different scaffolds have been prepared and investigated as carbonic anhydrase inhibitors, showing that some of them are very potent and selective CAIs. This article will review the latest developments in the synthesis and biological activity of these C-glycosides.
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Identificadores
Colecciones
Articulos(CCT - LA PLATA)
Articulos de CTRO.CIENTIFICO TECNOL.CONICET - LA PLATA
Articulos de CTRO.CIENTIFICO TECNOL.CONICET - LA PLATA
Citación
Martínez, Helberth Llantén; Riafrecha, Leonardo Ezequiel; Colinas, Pedro Alfonso; C-cinnamoyl glycosides: An emerging “Tail” for the development of selective carbonic anhydrase inhibitors; Bentham Science Publishers; Current Medicinal Chemistry; 26; 15; 7-2019; 2601-2608
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