LUCAS NICOLÁS ALBERCA

Datos académicos

Lugar de trabajo	UNIVERSIDAD NACIONAL DE LA PLATA / FACULTAD DE CS.EXACTAS / DEPARTAMENTO DE CS.BIOLOGICAS / CATEDRA DE QUIMICA MEDICINAL
Título	Doctor de la Facultad de Ciencias Exactas
Grado	Universitario de posgrado/doctorado
Campo de aplicación	Salud humana
Especialidad	Quimica Medicinal

PRODUCCION CIENTÍFICO TECNOLÓGICA

Mostrando ítems 1-20 de 28

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Artículo A combined ligand and target-based virtual screening strategy to repurpose drugs as putrescine uptake inhibitors with trypanocidal activity

Llanos, Manuel A.; Alberca, Lucas Nicolás ; Ruiz, María Daniela ; Sbaraglini, María L.; Miranda, Cristian Gabriel ; Pino Martínez, Agustina María ; Fraccaroli, Laura Virginia ; Carrillo, Carolina ; Alba Soto, Catalina Dirney ; Gavernet, Luciana ; Talevi, Alan (Springer, 2022-12)
Evento A versatile CRISPR/Cas9 editing approach in Trypanosoma cruzi

Vilchez Larrea, Salomé Catalina ; Prego, Alejo Facundo ; Schoijet, Alejandra Cecilia ; Llanos, Manuel ; Alberca, Lucas Nicolás ; Bellera, Carolina Leticia ; Gavernet, Luciana ; Talevi, Alan ; Alonso, Guillermo Daniel (Universidad Nacional de Cuyo, 2022)
Evento Antiproliferative effect of triclabendazole and clofazimine on Toxoplasma gondii growth, a repurposing approach

Ganuza, Agustina; Alberca, Lucas Nicolás ; Dietrich, Roque Carlos ; Gavernet, Luciana ; Talevi, Alan ; Corvi, Maria Martha (Fundación Revista Medicina, 2019)
Artículo Application of target repositioning and in silico screening to exploit fatty acid binding proteins (FABPs) from Echinococcus multilocularis as possible drug targets

Bélgamo, Julián Alberto ; Alberca, Lucas Nicolás ; Pórfido, Jorge Luis ; Caram Romero, Franco Nahuel ; Rodríguez, Santiago ; Talevi, Alan ; Córsico, Betina ; Franchini, Gisela Raquel (Springer, 2020-10)
Tesis Búsqueda asistida por computadora de nuevos fármacos antichagásicos análogos de poliaminas

Alberca, Lucas Nicolás (2018-12-21) Director: Talevi, Alan ; Codirector: Carrillo, Carolina
Artículo Cascade ligand- and structure-based virtual screening to identify new trypanocidal compounds inhibiting putrescine uptake

Alberca, Lucas Nicolás ; Sbaraglini, Maria Laura ; Morales, Juan Francisco ; Dietrich, Roque Carlos ; Ruiz, María Daniela ; Pino Martínez, Agustina María ; Miranda, Cristian Gabriel ; Fraccaroli, Laura Virginia ; Alba Soto, Catalina Dirney ; Carrillo, Carolina ; Palestro, Pablo Hernán ; Talevi, Alan (Frontiers Media SA, 2018-05)
Evento Discovery of novel falcipain 2 inhibitors by in silico guided drug repositioning

Alberca, Lucas Nicolás ; Chuguransky, Sara Rocío ; Alvarez, Cora Lilia ; Salas Sarduy, Emir ; Talevi, Alan (University of Dundee, 2019)
Artículo Discovery of novel polyamine analogs with anti-protozoal activity by computer guided drug repositioning

Alberca, Lucas Nicolás ; Sbaraglini, Maria Laura ; Balcazar, Dario Emmanuel ; Fraccaroli, Laura Virginia ; Carrillo, Carolina ; Medeiros, Andrea; Benitez, Diego; Comini, Marcelo; Talevi, Alan (Springer, 2016-04)
Artículo Drug repurposing screening validated by experimental assays identifies two clinical drugs targeting SARS-CoV-2 main protease

Prada Gori, Denis Nihuel ; Ruatta Merke, Santiago Matías; Fló, Martín; Alberca, Lucas Nicolás ; Bellera, Carolina Leticia ; Park, Soonju; Heo, Jinyeong; Lee, Honggun; Park, Kyu Ho Paul; Otto Pritsch; Shum, David; Comini, Marcelo A.; Talevi, Alan (Frontiers Media, 2023-01)
Evento Druggability assessment algorithm based on Composition, Transition and Distribution descriptors and publicly available predictive tools

Alice, Juan Ignacio ; Rodríguez, Santiago; Alberca, Lucas Nicolás ; Bellera, Carolina Leticia ; Talevi, Alan (Asociación Argentina de Bioinformática y Biología Computacional, 2021)
Evento Effect of putative PARG inhibitors identified by an in silico approach on Trypanosoma cruzi infection

Svagzdys, Ailin; Vilchez Larrea, Salomé Catalina ; Alberca, Lucas Nicolás ; Caram, Franco; Talevi, Alan ; Fernandez Villamil, Silvia Hebe (Fundación Revista Medicina, 2019)
Artículo Homology modeling and molecular dynamics simulations of Trypanosoma cruzi phosphodiesterase b1

Llanos, Manuel ; Alberca, Lucas Nicolás ; Vilchez Larrea, Salomé Catalina ; Schoijet, Alejandra Cecilia ; Alonso, Guillermo Daniel ; Bellera, Carolina Leticia ; Gavenet, Luciana; Talevi, Alan (Wiley VCH Verlag, 2022-01)
Artículo Identification of cisapride as new inhibitor of putrescine uptake in Trypanosoma cruzi by combined ligand- and structure-based virtual screening

Dietrich, Roque Carlos ; Alberca, Lucas Nicolás ; Ruiz, María Daniela ; Palestro, Pablo Hernán ; Carrillo, Carolina ; Talevi, Alan ; Gavernet, Luciana (Elsevier France-editions Scientifiques Medicales Elsevier, 2018-04-10)
Artículo In silico drug repositioning for chagas disease

Bellera, Carolina Leticia ; Alberca, Lucas Nicolás ; Sbaraglini, Maria Laura ; Talevi, Alan (Bentham Science Publishers, 2020)
Artículo In silico Guided Drug Repurposing: Discovery of New Competitive and Non-competitive Inhibitors of Falcipain-2

Alberca, Lucas Nicolás ; Chuguransky, Sara Rocío ; Alvarez, Cora Lilia ; Talevi, Alan ; Salas Sarduy, Emir (Frontiers Media S.A., 2019-08-06)
Capítulo de Libro In silico modeling of FDA-approved drugs for discovery of therapies against neglected diseases: A drug repurposing approach

Título del libro: In silico drug design methods for drug repurposing

Bellera, Carolina Leticia ; Sbaraglini, Maria Laura ; Alberca, Lucas Nicolás ; Alice, Juan Ignacio ; Talevi, Alan - Otros responsables: Kunal, Roy - (Elsevier, 2019)
Evento In silico-guided drug repurposing: identification of non-competitive inhibitors of Trypanosoma cruzi and Plasmodium falciparum cysteine proteases

Salas Sarduy, Emir ; Alberca, Lucas Nicolás ; Bellera, Carolina Leticia ; Talevi, Alan (Fundación Revista Medicina, 2020)
Artículo Integrated application of enhanced replacement method and ensemble learning for the prediction of BCRP/ABCG2 substrates

Gantner, Melisa Edith ; Alberca, Lucas Nicolás ; Mercader, Andrew Gustavo ; Bruno Blanch, Luis Enrique; Talevi, Alan (Bentham Science Publishers, 2017-06)
Artículo iRaPCA and SOMoC: Development and Validation of Web Applications for New Approaches for the Clustering of Small Molecules

Prada Gori, Denis Nihuel ; Llanos, Manuel ; Bellera, Carolina Leticia ; Talevi, Alan ; Alberca, Lucas Nicolás (American Chemical Society, 2022-06)
Artículo LIDeB Tools: A Latin American resource of freely available, open-source cheminformatics apps

Prada Gori, Denis Nihuel ; Alberca, Lucas Nicolás ; Rodríguez, Santiago ; Alice, Juan Ignacio ; Llanos, Manuel ; Bellera, Carolina Leticia ; Talevi, Alan (Elsevier, 2022-12)

Mostrando ítems 1-20 de 28

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