Evaluation of biomarkers in glioma by immunohistochemistry on paraffin- embedded 3D glioma neurosphere cultures | ||
| dc.conicet.fuente | individual | |
| dc.conicet.organizacion | University of Michigan | |
| dc.conicet.organizacion | University of Michigan | |
| dc.conicet.organizacion | University of Michigan | |
| dc.conicet.organizacion | Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones Bioquímicas de La Plata "Prof. Dr. Rodolfo R. Brenner". Universidad Nacional de la Plata. Facultad de Ciencias Médicas. Instituto de Investigaciones Bioquímicas de La Plata "Prof. Dr. Rodolfo R. Brenner" | |
| dc.conicet.organizacion | University of Michigan | |
| dc.conicet.organizacion | University of Michigan | |
| dc.conicet.organizacion | University of Michigan | |
| dc.conicet.organizacion | University of Michigan | |
| dc.conicet.paisOrganizacion | Estados Unidos | |
| dc.conicet.paisOrganizacion | Estados Unidos | |
| dc.conicet.paisOrganizacion | Estados Unidos | |
| dc.conicet.paisOrganizacion | Argentina | |
| dc.conicet.paisOrganizacion | Estados Unidos | |
| dc.conicet.paisOrganizacion | Estados Unidos | |
| dc.conicet.paisOrganizacion | Estados Unidos | |
| dc.conicet.paisOrganizacion | Estados Unidos | |
| dc.conicet.produccionid | 8075969 | |
| dc.contributor.author | Núñez Aguilera, Felipe Javier | |
| dc.contributor.author | Mendez, Flor M. | |
| dc.contributor.author | Garcia Fabbiani, María B. | |
| dc.contributor.author | Pardo, Joaquin | |
| dc.contributor.author | Edwards, Marta | |
| dc.contributor.author | Lowenstein, Pedro R. | |
| dc.contributor.author | Castro, María G. | |
| dc.date.accessioned | 2021-01-13T21:21:39Z | |
| dc.date.available | 2021-01-13T21:21:39Z | |
| dc.date.issued | 2019-01-09 | |
| dc.date.updated | 2020-11-25T17:35:41Z | |
| dc.description.abstract | Analysis of protein expression in glioma is relevant for several aspects in the study of its pathology. Numerous proteins have been described asbiomarkers with applications in diagnosis, prognosis, classification, state of tumor progression, and cell differentiation state. These analyses ofbiomarkers are also useful to characterize tumor neurospheres (NS) generated from glioma patients and glioma models. Tumor NS provide avaluable in vitro model to assess different features of the tumor from which they are derived and can more accurately mirror glioma biology. Herewe describe a detailed method to analyze biomarkers in tumor NS using immunohistochemistry (IHC) on paraffin-embedded tumor NS. | es |
| dc.description.fil | Fil: Núñez Aguilera, Felipe Javier. University of Michigan; Estados Unidos | |
| dc.description.fil | Fil: Mendez, Flor M.. University of Michigan; Estados Unidos | |
| dc.description.fil | Fil: Garcia Fabbiani, María B.. University of Michigan; Estados Unidos | |
| dc.description.fil | Fil: Pardo, Joaquin. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones Bioquímicas de La Plata "Prof. Dr. Rodolfo R. Brenner". Universidad Nacional de la Plata. Facultad de Ciencias Médicas. Instituto de Investigaciones Bioquímicas de La Plata "Prof. Dr. Rodolfo R. Brenner"; Argentina. University of Michigan; Estados Unidos | |
| dc.description.fil | Fil: Edwards, Marta. University of Michigan; Estados Unidos | |
| dc.description.fil | Fil: Lowenstein, Pedro R.. University of Michigan; Estados Unidos | |
| dc.description.fil | Fil: Castro, María G.. University of Michigan; Estados Unidos | |
| dc.format | application/pdf | es |
| dc.identifier.citation | Núñez Aguilera, Felipe Javier; Mendez, Flor M.; Garcia Fabbiani, María B.; Pardo, Joaquin; Edwards, Marta; et al.; Evaluation of biomarkers in glioma by immunohistochemistry on paraffin- embedded 3D glioma neurosphere cultures; MyJoVE Corporation; Journal of Visualized Experiments; 2019; 143; 9-1-2019; 1-7 | es |
| dc.identifier.institucional | CONICET | |
| dc.identifier.issn | 1940-087X | es |
| dc.identifier.repo | CONICET Digital | |
| dc.identifier.uri | http://hdl.handle.net/11336/122684 | |
| dc.journal.number | 143 | es |
| dc.journal.pagination | 1-7 | es |
| dc.journal.pais | Estados Unidos | es |
| dc.journal.title | Journal of Visualized Experiments | es |
| dc.journal.volume | 2019 | es |
| dc.language.iso | eng | es |
| dc.publisher | MyJoVE Corporation | es |
| dc.relation.alternativeid | info:eu-repo/semantics/altIdentifier/url/https://www.jove.com/video/58931/evaluation-biomarkers-glioma-immunohistochemistry-on-paraffin | |
| dc.relation.alternativeid | info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.3791/58931 | |
| dc.rights | info:eu-repo/semantics/restrictedAccess | * |
| dc.rights.uri | https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ | * |
| dc.subject | 3D-CULTURES | es |
| dc.subject | BIOMARKERS | es |
| dc.subject | CANCER RESEARCH | es |
| dc.subject | GENETICALLY ENGINEERED | es |
| dc.subject | GLIOMA | es |
| dc.subject | IMMUNOSTAINING | es |
| dc.subject | ISSUE 143 | es |
| dc.subject | NEUROSPHERES | es |
| dc.subject | PARAFFIN EMBEDDING | es |
| dc.subject.classification | Otras Ciencias Biológicas | es |
| dc.subject.classification | Ciencias Biológicas | es |
| dc.subject.classification | CIENCIAS NATURALES Y EXACTAS | es |
| dc.title | Evaluation of biomarkers in glioma by immunohistochemistry on paraffin- embedded 3D glioma neurosphere cultures | es |
| dc.type | info:eu-repo/semantics/article | |
| dc.type | info:ar-repo/semantics/artículo | |
| dc.type | info:eu-repo/semantics/publishedVersion | |
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