Transcriptional Regulation of Oncogenic Protein Kinase Cϵ (PKCϵ) by STAT1 and Sp1 Proteins | ||
| dc.conicet.fuente | unificacion | |
| dc.conicet.organizacion | University of Pennsylvania | |
| dc.conicet.organizacion | University of Pennsylvania | |
| dc.conicet.organizacion | University of Pennsylvania | |
| dc.conicet.organizacion | University of Pennsylvania | |
| dc.conicet.organizacion | University of Pennsylvania | |
| dc.conicet.organizacion | University of Pennsylvania | |
| dc.conicet.organizacion | University of Pennsylvania | |
| dc.conicet.organizacion | University of Pennsylvania | |
| dc.conicet.organizacion | Consejo Nacional de Investigaciones Científicas y Técnicas | |
| dc.conicet.organizacion | Universidad Nacional de La Plata. Facultad de Ciencias Médicas. Centro de Investigaciones Inmunológicas Básicas y Aplicadas | |
| dc.conicet.organizacion | University of Pennsylvania | |
| dc.conicet.paisOrganizacion | Estados Unidos | |
| dc.conicet.paisOrganizacion | Estados Unidos | |
| dc.conicet.paisOrganizacion | Estados Unidos | |
| dc.conicet.paisOrganizacion | Estados Unidos | |
| dc.conicet.paisOrganizacion | Estados Unidos | |
| dc.conicet.paisOrganizacion | Estados Unidos | |
| dc.conicet.paisOrganizacion | Estados Unidos | |
| dc.conicet.paisOrganizacion | Estados Unidos | |
| dc.conicet.paisOrganizacion | Argentina | |
| dc.conicet.paisOrganizacion | Argentina | |
| dc.conicet.paisOrganizacion | Estados Unidos | |
| dc.conicet.produccionid | 5405804 | |
| dc.contributor.author | Wang, HongBin | |
| dc.contributor.author | Gutierrez Uzquiza, Alvaro | |
| dc.contributor.author | Garg, Rachana | |
| dc.contributor.author | Barrio Real, Laura | |
| dc.contributor.author | Abera, Mahlet B | |
| dc.contributor.author | Lopez Haber, Cynthia | |
| dc.contributor.author | Rosemblit, Cinthia | |
| dc.contributor.author | Lu, Huaisheng | |
| dc.contributor.author | Abba, Martín Carlos | |
| dc.contributor.author | Kazanietz, Marcelo G. | |
| dc.date.accessioned | 2018-01-11T17:06:50Z | |
| dc.date.available | 2018-01-11T17:06:50Z | |
| dc.date.issued | 2014-07 | |
| dc.date.updated | 2018-01-08T18:43:14Z | |
| dc.description.abstract | Background: PKCϵ, a kinase widely implicated in tumorigenesis and metastasis, is overexpressed in many cancers. Results: Transcription factors Sp1 and STAT1 control the expression of PKCϵ in cancer cells. Conclusion: Up-regulation of PKCϵ is mediated by dysregulated transcriptional mechanisms. Significance: Our results may have significant implications for the development of approaches to target PKCϵ and its effectors in cancer therapeutics. | es |
| dc.description.fil | Fil: Wang, HongBin. University of Pennsylvania; Estados Unidos | |
| dc.description.fil | Fil: Gutierrez Uzquiza, Alvaro. University of Pennsylvania; Estados Unidos | |
| dc.description.fil | Fil: Garg, Rachana. University of Pennsylvania; Estados Unidos | |
| dc.description.fil | Fil: Barrio Real, Laura. University of Pennsylvania; Estados Unidos | |
| dc.description.fil | Fil: Abera, Mahlet B. University of Pennsylvania; Estados Unidos | |
| dc.description.fil | Fil: Lopez Haber, Cynthia. University of Pennsylvania; Estados Unidos | |
| dc.description.fil | Fil: Rosemblit, Cinthia. University of Pennsylvania; Estados Unidos | |
| dc.description.fil | Fil: Lu, Huaisheng. University of Pennsylvania; Estados Unidos | |
| dc.description.fil | Fil: Abba, Martín Carlos. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Médicas. Centro de Investigaciones Inmunológicas Básicas y Aplicadas; Argentina | |
| dc.description.fil | Fil: Kazanietz, Marcelo G.. University of Pennsylvania; Estados Unidos | |
| dc.format | application/pdf | es |
| dc.identifier.citation | Lopez Haber, Cynthia; Garg, Rachana; Rosemblit, Cinthia; Abera, Mahlet B; Gutierrez Uzquiza, Alvaro; Kazanietz, Marcelo G.; et al.; Transcriptional Regulation of Oncogenic Protein Kinase Cϵ (PKCϵ) by STAT1 and Sp1 Proteins; American Society for Biochemistry and Molecular Biology; Journal Of Biological Chemistry (online); 289; 7-2014; 19823-19838 | es |
| dc.identifier.institucional | CONICET | |
| dc.identifier.issn | 1083-351X | es |
| dc.identifier.repo | CONICET Digital | |
| dc.identifier.uri | http://hdl.handle.net/11336/32973 | |
| dc.journal.pagination | 19823-19838 | es |
| dc.journal.pais | Estados Unidos | es |
| dc.journal.title | Journal Of Biological Chemistry (online) | es |
| dc.journal.volume | 289 | es |
| dc.language.iso | eng | es |
| dc.publisher | American Society for Biochemistry and Molecular Biology | es |
| dc.relation.alternativeid | info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1074/jbc.M114.548446 | |
| dc.relation.alternativeid | info:eu-repo/semantics/altIdentifier/url/http://www.jbc.org/content/289/28/19823 | |
| dc.rights | info:eu-repo/semantics/openAccess | * |
| dc.rights.uri | https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ | * |
| dc.subject | Breast Cancer | es |
| dc.subject | Diacylglycerol | es |
| dc.subject | Gene Expression | es |
| dc.subject | Protein Kinase C Epsilon | es |
| dc.subject.classification | Otras Ciencias Biológicas | es |
| dc.subject.classification | Ciencias Biológicas | es |
| dc.subject.classification | CIENCIAS NATURALES Y EXACTAS | es |
| dc.title | Transcriptional Regulation of Oncogenic Protein Kinase Cϵ (PKCϵ) by STAT1 and Sp1 Proteins | es |
| dc.type | info:eu-repo/semantics/article | |
| dc.type | info:ar-repo/semantics/artículo | |
| dc.type | info:eu-repo/semantics/publishedVersion | |
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