Artículo
Potential use of medicinal plants from Argentinean highland as agent anti-photoaging
Orqueda, Maria Eugenia
; Moreno, María Alejandra
; Zampini, Iris Catiana
; Bravo, Karent; Osorio, Edison; Isla, Maria Ines
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Fecha de publicación:
04/2021
Editorial:
John Wiley & Sons Inc
Revista:
Journal of Cosmetic Dermatology
ISSN:
1473-2165
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
Background: The overexposure to sun ultraviolet (UV) radiation produce photoaging by effect of free radicals on lipid, protein, and nucleic acid or by direct activation of responsible enzymes of cleavage of extracellular matrix components (EMC). Aims: To develop new anti-photoaging agents, the anti-aging activity of four “jarillas” standardized extracts from Argentina (Zuccagnia punctata Cav., Larrea divaricata Cav., Larrea cuneifolia Cav., and Larrea nitida Cav.) were examined. Methods: The effect on the activity and expression of enzymes related to photoaging (collagenase, hyaluronidase, elastase, tyrosinase) and the antioxidant capacity of four “jarillas” extracts were examined. Results: The results suggest that “jarillas” extracts could protect EMC by inhibition of skin aging-related enzymes and suppression of the expression of metalloproteinases (MMP-1) in human skin fibroblasts from photoinduced damage. Modulation of MMP-1 expression induced by UV radiation in human skin cells could be associated, at least in part, with the ROS scavenging capacity of “jarilla” extracts. The extract of Z punctata was more active than Larrea species extracts in all the trials. The activity of Z punctata and Larrea extracts could be ascribed to chalcones and lignans, major constituents of “jarillas,” respectively. Conclusions: The results obtained would indicate the potential of these adapted species to live in arid zones of Argentina, exposed to high ultraviolet radiation in production of cosmetic products and justify the promotion of their sustainable use and the development of crops.
Palabras clave:
ARGENTINIAN “JARILLAS”
,
COLLAGENASE
,
ELASTASE
,
HYALURONIDASE
,
PHOTOAGING
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Citación
Orqueda, Maria Eugenia; Moreno, María Alejandra; Zampini, Iris Catiana; Bravo, Karent; Osorio, Edison; et al.; Potential use of medicinal plants from Argentinean highland as agent anti-photoaging; John Wiley & Sons Inc; Journal of Cosmetic Dermatology; 20; 4; 4-2021; 1188-1196
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