Botryomycosis in Nod.cgprkdcscid il2rgtm1wjl/szj mice: A focal outbreak in an experimental colony

Abstract

NOD.Cg-PrkdcscidIl2rgtm1Wjl/SzJ mice were purchased from Jackson Laboratory and maintained under conventional closed barriers in individually ventilated cages (Tecniplast®) with controlled temperature (20-22°) and relative humidity (50-70%) in a 12:12 h light: dark cycle. The animals were fed with autoclaved standard diet and carbon activated filtered water ad libitum. Cages were filled with sterile wooden chips and corn. The experimental protocols were approved by the IACUC.