Galectins as immunoregulators during infectious processes: from microbial invasion to the resolution of the disease

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dc.conicet.fuenteunificacion
dc.conicet.organizacionUniversidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas General San Martín
dc.conicet.organizacionConsejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental
dc.conicet.organizacionConsejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Centro de Investigaciones en Bioquímica Clínica e Inmunología
dc.conicet.paisOrganizacionArgentina
dc.conicet.paisOrganizacionArgentina
dc.conicet.paisOrganizacionArgentina
dc.conicet.produccionid6537740
dc.contributor.authorRabinovich, Gabriel Adrián
dc.contributor.authorGruppi, Adriana
dc.date.accessioned2017-12-23T21:52:53Z
dc.date.available2017-12-23T21:52:53Z
dc.date.issued2005-05-22
dc.date.updated2017-12-19T18:47:44Z
dc.description.abstractRecent evidence has implicated galectins, a family of evolutionarily conserved carbohydrate-binding proteins, as regulators of immune cell homeostasis and host-pathogen interactions. Galectins operate at different levels of innate and adaptive immune responses, by modulating cell survival and cell activation or by influencing the Th1/Th2 cytokine balance. Furthermore, galectins may contribute to host-pathogen recognition and may serve as receptors for specific interactions of pathogens with their insect vectors. Here we will explore the influence of galectins in immunological processes relevant to microbial infection and will summarize exciting recent work related to the specific interactions between galectins and their glycoconjugate ligands as critical determinants of pathogen recognition. Understanding the role of galectin-sugar interactions during the course of microbial infections might contribute to defining novel targets for disease prevention and immune intervention.es
dc.description.filFil: Rabinovich, Gabriel Adrián. Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas General San Martín; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina
dc.description.filFil: Gruppi, Adriana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Centro de Investigaciones en Bioquímica Clínica e Inmunología; Argentina
dc.formatapplication/pdfes
dc.identifier.citationGruppi, Adriana; Rabinovich, Gabriel Adrián; Galectins as immunoregulators during infectious processes: from microbial invasion to the resolution of the disease; Wiley Blackwell Publishing, Inc; Parasite Immunology; 27; 4; 22-5-2005; 103-114es
dc.identifier.eissn1365-3024es
dc.identifier.institucionalCONICET
dc.identifier.issn0141-9838es
dc.identifier.repoCONICET Digital
dc.identifier.urihttp://hdl.handle.net/11336/31473
dc.journal.ciudadOxfordes
dc.journal.number4es
dc.journal.pagination103-114es
dc.journal.paisReino Unidoes
dc.journal.titleParasite Immunologyes
dc.journal.volume27es
dc.language.isoenges
dc.publisherWiley Blackwell Publishing, Inces
dc.relation.alternativeidinfo:eu-repo/semantics/altIdentifier/url/http://onlinelibrary.wiley.com/doi/10.1111/j.1365-3024.2005.00749.x/abstract
dc.relation.alternativeidinfo:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1111/j.1365-3024.2005.00749.x
dc.relation.alternativeidinfo:eu-repo/semantics/altIdentifier/pmid/15910418
dc.relation.alternativeidinfo:eu-repo/semantics/altIdentifier/url/http://europepmc.org/abstract/med/15910418
dc.rightsinfo:eu-repo/semantics/openAccess*
dc.rights.urihttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/*
dc.subjectGalectinses
dc.subjectInfectiones
dc.subjectParasiteses
dc.subjectImmuneregulationes
dc.subject.classificationInmunologíaes
dc.subject.classificationMedicina Básicaes
dc.subject.classificationCIENCIAS MÉDICAS Y DE LA SALUDes
dc.titleGalectins as immunoregulators during infectious processes: from microbial invasion to the resolution of the diseasees
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:ar-repo/semantics/artículo
dc.typeinfo:eu-repo/semantics/publishedVersion

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