Population genetic analyses of the Powerplex Fusion kit in a cosmopolitan sample of Chubut province (Patagonia Argentina)

Abstract

Allele frequencies and forensic parameters for 22 autosomal STR loci and DYS391 locus included in the PowerPlex® Fusion System kit were estimated in a sample of 770 unrelated individuals from Chubut province, southern Patagonia. No significant deviations from Hardy-Weinberg equilibrium were observed after Bonferroni?s correction. The combined power of discrimination and the combined probability of exclusion were >0.999999 and 0.999984, respectively. Comparisons with other worldwide populations were performed. The MDS obtained show a close biological relation between Chubut and Chile. The estimated interethnic admixture supports a high Native American contribution (46%) in the population sample of Chubut. These results enlarge the Argentine databases of autosomal STR and would provide a valuable contribution for identification tests and population genetic studies.