The metabolic-immune axis in MASH: is the macrophage signature the key to liver disease staging? | ||
| dc.conicet.fuente | Crossref | |
| dc.conicet.organizacion | Consejo Nacional de Investigaciones Científicas y Técnicas | |
| dc.conicet.organizacion | Universidad Maimónides. Facultad de Ciencias de la Salud. Centro de Investigación Traslacional en Salud | |
| dc.conicet.paisOrganizacion | Argentina | |
| dc.conicet.paisOrganizacion | ||
| dc.conicet.produccionid | 13199679 | |
| dc.contributor.author | Pirola, Carlos Jose | |
| dc.date.accessioned | 2026-07-27T12:16:22Z | |
| dc.date.available | 2026-07-27T12:16:22Z | |
| dc.date.issued | 2026-07 | |
| dc.date.updated | 2026-07-23T12:27:12Z | |
| dc.description.abstract | The evolving paradigm of macrophage-centered MASH diagnostics. Macrophage plasticity, metabolic stress, mitochondrial heteroplasmy, and TGF-β signaling converge to develop MASH. This signature (CPM, PTK2B, FRMD4B, SPTLC2, and EPB41L2) may move beyond mere description to offer causally inferable, high-precision non-invasive biomarkers for disease staging. | es |
| dc.description.fil | Fil: Pirola, Carlos Jose. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Maimónides. Facultad de Ciencias de la Salud. Centro de Investigación Traslacional en Salud; | |
| dc.format | application/pdf | es |
| dc.identifier.citation | Pirola, Carlos Jose; The metabolic-immune axis in MASH: is the macrophage signature the key to liver disease staging?; American Society for Biochemistry and Molecular Biology; Journal of Lipid Research Papers In Press; 67; 8; 7-2026; 1-3 | es |
| dc.identifier.eissn | 1539-7262 | es |
| dc.identifier.institucional | CONICET | |
| dc.identifier.issn | 0022-2275 | es |
| dc.identifier.repo | CONICET Digital | |
| dc.identifier.uri | http://hdl.handle.net/11336/293222 | |
| dc.journal.ciudad | Bethesda | es |
| dc.journal.number | 8 | es |
| dc.journal.pagination | 1-3 | es |
| dc.journal.pais | Estados Unidos | es |
| dc.journal.title | Journal of Lipid Research Papers In Press | es |
| dc.journal.volume | 67 | es |
| dc.language.iso | eng | es |
| dc.publisher | American Society for Biochemistry and Molecular Biology | es |
| dc.relation.alternativeid | info:eu-repo/semantics/altIdentifier/url/https://linkinghub.elsevier.com/retrieve/pii/S0022227526001264 | |
| dc.relation.alternativeid | info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.jlr.2026.101096 | |
| dc.rights | info:eu-repo/semantics/openAccess | * |
| dc.rights.uri | https://creativecommons.org/licenses/by/2.5/ar/ | * |
| dc.subject | MASLD | es |
| dc.subject | SNRNASEQ | es |
| dc.subject | MACROPHAGES | es |
| dc.subject | INFLAMMATION | es |
| dc.subject | MASH | es |
| dc.subject.classification | Bioquímica y Biología Molecular | es |
| dc.subject.classification | Medicina Básica | es |
| dc.subject.classification | CIENCIAS MÉDICAS Y DE LA SALUD | es |
| dc.subject.classification | Gastroenterología y Hepatología | es |
| dc.subject.classification | Medicina Clínica | es |
| dc.subject.classification | CIENCIAS MÉDICAS Y DE LA SALUD | es |
| dc.subject.classification | Otras Medicina Clínica | es |
| dc.subject.classification | Medicina Clínica | es |
| dc.subject.classification | CIENCIAS MÉDICAS Y DE LA SALUD | es |
| dc.title | The metabolic-immune axis in MASH: is the macrophage signature the key to liver disease staging? | es |
| dc.type | info:eu-repo/semantics/article | |
| dc.type | info:ar-repo/semantics/artículo | |
| dc.type | info:eu-repo/semantics/publishedVersion | |
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