Clinical Applications of RNA Editing Technology for the Early Detection of Cancer and Future Directions

Volver a la Vista simple
dc.conicet.fuenteCrossref
dc.conicet.organizacionUniversity of Stanford
dc.conicet.organizacionUniversity of Stanford
dc.conicet.organizacionConsejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Medicina Traslacional, Trasplante y Bioingeniería. Fundación Favaloro. Instituto de Medicina Traslacional, Trasplante y Bioingeniería
dc.conicet.paisOrganizacionEstados Unidos
dc.conicet.paisOrganizacionEstados Unidos
dc.conicet.paisOrganizacionArgentina
dc.conicet.produccionid9117478
dc.contributor.authorMujib, Ullah
dc.contributor.authorAsma, Akbar
dc.contributor.authorYannarelli, Gustavo Gabriel
dc.date.accessioned2021-04-22T13:36:42Z
dc.date.available2021-04-22T13:36:42Z
dc.date.issued2020-01
dc.date.updated2021-03-26T19:53:14Z
dc.description.abstractEarly detection of cancer has great clinical importance and potentially improves cure, survival rate and treatment outcome. RNA editing technology can be used as targeted and precise molecular scissors to cut and replace disease-causing genes with healthy ones. This is a post transcriptional modification that can lead to the recoding of proteins. RNA editing technology is in its infancy, but it can be used for early diagnoses and effective treatment of cancer. The full potential of precision medicine will be achieved by using the knowledge of RNA reversible-recoding to edit the protein. RNA editing technology could be used to expose chemo resistant cancer cells, dormant cancer stem cells and other malignant tumors. RNA editing generates RNA and protein diversity to accelerate and enhance the screening window for early detection of cancer. We propose that the RNA editing sites could be used as a novel tool for early detection of cancer.es
dc.description.filFil: Mujib, Ullah. University of Stanford; Estados Unidos
dc.description.filFil: Asma, Akbar. University of Stanford; Estados Unidos
dc.description.filFil: Yannarelli, Gustavo Gabriel. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Medicina Traslacional, Trasplante y Bioingeniería. Fundación Favaloro. Instituto de Medicina Traslacional, Trasplante y Bioingeniería; Argentina
dc.formatapplication/pdfes
dc.identifier.citationMujib, Ullah; Asma, Akbar; Yannarelli, Gustavo Gabriel; Clinical Applications of RNA Editing Technology for the Early Detection of Cancer and Future Directions; SAGE Publications; Technology In Cancer Research & Treatment; 19; 1-2020; 1-4es
dc.identifier.eissn1533-0338es
dc.identifier.institucionalCONICET
dc.identifier.issn1533-0346es
dc.identifier.repoCONICET Digital
dc.identifier.urihttp://hdl.handle.net/11336/130710
dc.journal.pagination1-4es
dc.journal.paisEstados Unidoses
dc.journal.titleTechnology In Cancer Research & Treatmentes
dc.journal.volume19es
dc.language.isoenges
dc.publisherSAGE Publicationses
dc.relation.alternativeidinfo:eu-repo/semantics/altIdentifier/url/http://journals.sagepub.com/doi/10.1177/1533033820964194
dc.relation.alternativeidinfo:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1177/1533033820964194
dc.rightsinfo:eu-repo/semantics/openAccess*
dc.rights.urihttps://creativecommons.org/licenses/by-nc/2.5/ar/*
dc.subjectRNA EDITINGes
dc.subjectCANCERes
dc.subjectDETECTIONes
dc.subject.classificationBiotecnología relacionada con la Saludes
dc.subject.classificationBiotecnología de la Saludes
dc.subject.classificationCIENCIAS MÉDICAS Y DE LA SALUDes
dc.titleClinical Applications of RNA Editing Technology for the Early Detection of Cancer and Future Directionses
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:ar-repo/semantics/artículo
dc.typeinfo:eu-repo/semantics/publishedVersion

Archivos

Bloque original

Miniatura
Nombre:
CONICET_Digital_Nro.dffdc2ba-6b99-4c6c-806f-9cb985ef5a89_A.pdf
Tamaño:
278.8 KB
Formato:
Adobe Portable Document Format
Descargar

Colecciones

Articulos (IMETTYB)
Volver a la Vista simple