Neonatal exposure to bisphenol a alters reproductive parameters and gonadotropin releasing hormone signaling in female rats

Abstract

Bisphenol A (BPA) is a component of polycarbonate plastics, epoxy resins, and polystyrene and is found in many products. Several reports have revealed potent in vivo effects, because BPA acts as an estrogen agonist and/or antagonist and as an androgen and thyroid hormone antagonist We analyzed the effects of neonatal exposure to BPA on the reproductive axis of female Sprague-Dawley rats.