Closed-loop control of epilepsy by transcranial electrical stimulation

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dc.conicet.fuenteindividual
dc.conicet.organizacionRutgers University
dc.conicet.organizacionUniversity of New York
dc.conicet.organizacionUniversity of Szeged
dc.conicet.organizacionConsejo Nacional de Investigaciones Científicas y Técnicas
dc.conicet.organizacionRutgers University
dc.conicet.organizacionRutgers University
dc.conicet.organizacionRutgers University
dc.conicet.organizacionUniversity of New York
dc.conicet.paisOrganizacionEstados Unidos
dc.conicet.paisOrganizacionEstados Unidos
dc.conicet.paisOrganizacionHungría
dc.conicet.paisOrganizacionArgentina
dc.conicet.paisOrganizacionEstados Unidos
dc.conicet.paisOrganizacionEstados Unidos
dc.conicet.paisOrganizacionEstados Unidos
dc.conicet.paisOrganizacionEstados Unidos
dc.conicet.produccionid5208378
dc.contributor.authorBerényi, Antal
dc.contributor.authorBelluscio, Mariano Andres
dc.contributor.authorMao, Dun
dc.contributor.authorBuzsáki, György
dc.date.accessioned2023-05-10T15:01:48Z
dc.date.available2023-05-10T15:01:48Z
dc.date.issued2012-08
dc.date.updated2023-05-09T14:47:18Z
dc.description.abstractMany neurological and psychiatric diseases are associated with clinically detectable, altered brain dynamics. The aberrant brain activity, in principle, can be restored through electrical stimulation. In epilepsies, abnormal patterns emerge intermittently, and therefore, a closed-loop feedback brain control that leaves other aspects of brain functions unaffected is desirable. Here, we demonstrate that seizure-triggered, feedback transcranial electrical stimulation (TES) can dramatically reduce spike-and-wave episodes in a rodent model of generalized epilepsy. Closed-loop TES can be an effective clinical tool to reduce pathological brain patterns in drug-resistant patients.es
dc.description.filFil: Berényi, Antal. Rutgers University; Estados Unidos. University of New York; Estados Unidos. University of Szeged; Hungría
dc.description.filFil: Belluscio, Mariano Andres. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Rutgers University; Estados Unidos
dc.description.filFil: Mao, Dun. Rutgers University; Estados Unidos
dc.description.filFil: Buzsáki, György. Rutgers University; Estados Unidos. University of New York; Estados Unidos
dc.formatapplication/pdfes
dc.identifier.citationBerényi, Antal; Belluscio, Mariano Andres; Mao, Dun; Buzsáki, György; Closed-loop control of epilepsy by transcranial electrical stimulation; American Association for the Advancement of Science; Science; 337; 6095; 8-2012; 735-737es
dc.identifier.institucionalCONICET
dc.identifier.issn0036-8075es
dc.identifier.repoCONICET Digital
dc.identifier.urihttp://hdl.handle.net/11336/196992
dc.journal.number6095es
dc.journal.pagination735-737es
dc.journal.paisEstados Unidoses
dc.journal.titleSciencees
dc.journal.volume337es
dc.language.isoenges
dc.publisherAmerican Association for the Advancement of Sciencees
dc.relation.alternativeidinfo:eu-repo/semantics/altIdentifier/url/http://www.sciencemag.org/content/337/6095/735.abstract
dc.relation.alternativeidinfo:eu-repo/semantics/altIdentifier/doi/https://doi.org/10.1126/science.1223154
dc.rightsinfo:eu-repo/semantics/openAccess*
dc.rights.urihttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/*
dc.subjectOscillationses
dc.subjectEpilepsyes
dc.subjectElectrical stimulationes
dc.subjectCortexes
dc.subject.classificationNeurocienciases
dc.subject.classificationMedicina Básicaes
dc.subject.classificationCIENCIAS MÉDICAS Y DE LA SALUDes
dc.titleClosed-loop control of epilepsy by transcranial electrical stimulationes
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:ar-repo/semantics/artículo
dc.typeinfo:eu-repo/semantics/publishedVersion

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