Percentilos del peso de la placenta y su relación con el peso fetal según la edad gestacional en el área urbana de Buenos Aires
; Dipierri, Jose Edgardo Otros responsables
Fecha
10/2015
Editorial
Universidad Nacional de Córdoba. Facultad de Ciencias Médicas
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Revista de la Facultad de Ciencias Médicas
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0014-6722
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Antecedentes: El peso placentario (PP) y los índices de su relación con el peso al nacer (PN)(PN/PP, PP/PN) predicen morbi-mortalidad perinatal y resultados alejados de la salud.Objetivos: Calcular percentilos del PP e índices por sexo y edad gestacional correspondientes a 867 RNV de la Maternidad Sardá de Buenos Aires, Argentina y compararlos con referencias internacionales.Material y métodos: Se excluyeron feto muerto, embarazo múltiple, edad gestacional <22 y >42 semanas y PP<100g y >2500g. Características maternas y fetales: edad, educación, tabaco, paridad, diabetes, preeclampsia, Corioamnionitis, restricción del crecimiento, malformación congénita y prematurez. Se calcularon estadísticos de resumen y percentilos con el métodoLMS. Las comparaciones se realizaron con test t-Student, ANOVA y referencias internacionales.Resultados: Edad materna media 24 años, educación 10.1 años, 24.5% primíparas, 12.6% fumadoras, 4.9% presentaron diabetes, 8.7% preeclampsia, 7.9% corioamnionitis y 13.0% restricción del crecimiento fetal. El 55.3% de los RN fueron varones, 51.6% prematuros, 18.9% PEG y 7.1% malformados. El PN y EG promedio fue de 2581g y 35.6 semanas respectivamente.Elevada correlación positiva de la EG con PP y PN/PP y negativa con PP/PN (p<0.001); el peso de la placenta e índices fueron mayores en varones. Se presentan los percentiles de PP, PN/PP y PP/PN. Las diferencias con las referencias oscilaron de 0.46% -13%, 4.91% -12.1% y 5.81% -14% para el PP, PN/PP y PP/PN respectivamente.Conclusiones: los percentilos generados son aplicables en investigaciones sobre la relación de la placenta con resultados perinatales y la salud durante el ciclo vital.
Background: The placental weight (PW) and the rates of their relationship with birth weight (BW) (BW / PW, PW / BW) predict perinatal morbidity and mortality and future health outcomes. Objectives: Estimate percentiles of PW and indices by sex and gestational age (GA) corresponding to 867 live born from Sardá Maternity of Buenos Aires and compare with international references. Methods: Stillbirth, multiple pregnancy, gestational age <22 and > 42 weeks and PW <100g and > 2500g were excluded. Maternal and fetal characteristics were: age, education, smoking, parity, diabetes, preeclampsia, chorioamnionitis, growth restriction, prematurity and congenital anomalies. Summary statistics and percentiles with the LMS method were calculated. The comparisons were performed using Student t-test, ANOVA and international references. Results: Average maternal age 24 years , education 10.1 years, 24.5% primiparous, 12.6% smokers, 4.9% had diabetes, 8.7% preeclampsia, 7.9% chorioamnionitis and 13.0% fetal growth restriction; 55.3% of newborns were male, 51.6% preterm, 18.9% small for gestational age and 7.1% malformed. On average BW and GA were 2581g and 35.6 weeks, respectively. High positive correlation between GA with PW and BW/PW, and negative with PW/BW was observed (p <0.001); placental weight and indices were higher in males. Percentiles of PW, BW / PW and PW / BW are depicted. Differences with references ranged from 0.46% -13%, 4.91% -12.1% and 5.81% -14% for PW, BW / PW and PW / BW, respectively. Conclusions: Percentiles generated are applicable in research on the relationship of the placenta with perinatal outcomes and health throughout the life cycle.
Background: The placental weight (PW) and the rates of their relationship with birth weight (BW) (BW / PW, PW / BW) predict perinatal morbidity and mortality and future health outcomes. Objectives: Estimate percentiles of PW and indices by sex and gestational age (GA) corresponding to 867 live born from Sardá Maternity of Buenos Aires and compare with international references. Methods: Stillbirth, multiple pregnancy, gestational age <22 and > 42 weeks and PW <100g and > 2500g were excluded. Maternal and fetal characteristics were: age, education, smoking, parity, diabetes, preeclampsia, chorioamnionitis, growth restriction, prematurity and congenital anomalies. Summary statistics and percentiles with the LMS method were calculated. The comparisons were performed using Student t-test, ANOVA and international references. Results: Average maternal age 24 years , education 10.1 years, 24.5% primiparous, 12.6% smokers, 4.9% had diabetes, 8.7% preeclampsia, 7.9% chorioamnionitis and 13.0% fetal growth restriction; 55.3% of newborns were male, 51.6% preterm, 18.9% small for gestational age and 7.1% malformed. On average BW and GA were 2581g and 35.6 weeks, respectively. High positive correlation between GA with PW and BW/PW, and negative with PW/BW was observed (p <0.001); placental weight and indices were higher in males. Percentiles of PW, BW / PW and PW / BW are depicted. Differences with references ranged from 0.46% -13%, 4.91% -12.1% and 5.81% -14% for PW, BW / PW and PW / BW, respectively. Conclusions: Percentiles generated are applicable in research on the relationship of the placenta with perinatal outcomes and health throughout the life cycle.
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