Phenotypic characterisation of mice with exaggerated and missing LH/hCG action

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dc.conicet.organizacionUniversity of Turku
dc.conicet.organizacionConsejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental
dc.conicet.organizacionUniversity of Turku
dc.conicet.organizacionUniversity of Helsinki
dc.conicet.organizacionUniversity of Turku
dc.conicet.organizacionUniversity of Turku
dc.conicet.organizacionImperial College London
dc.conicet.paisOrganizacionFinlandia
dc.conicet.paisOrganizacionArgentina
dc.conicet.paisOrganizacionFinlandia
dc.conicet.paisOrganizacionFinlandia
dc.conicet.paisOrganizacionFinlandia
dc.conicet.paisOrganizacionFinlandia
dc.conicet.paisOrganizacionReino Unido
dc.conicet.produccionid6298668
dc.contributor.authorAhtiainen, Petteri
dc.contributor.authorRulli, Susana Beatriz
dc.contributor.authorPakarainen, Tomi
dc.contributor.authorZhang, Fu-Ping
dc.contributor.authorPoutanen, Matti
dc.contributor.authorHuhtaniemi, Ilpo
dc.date.accessioned2017-11-02T23:14:39Z
dc.date.available2017-11-02T23:14:39Z
dc.date.issued2007-01
dc.date.updated2017-10-12T19:48:49Z
dc.description.abstractIn order to study the physiology and pathophysiology of gonadotrophin action, we have produced transgenic (TG) mice overexpressing human chorionic gonadotrophin (hCG) alpha and beta subunits (hCG+ mice) and knockout (KO) mice for the luteinising hormone receptor (LHR; LuRKO mice). The two extremes in LH function, i.e. strong LH/hCG stimulation and total blockade of this action, confirm numerous earlier concepts about LH function, but they also reveal new aspects about gonadal function during excessive LH production and in the absence of this trophic stimulus. The purpose of this review is to summarise the key findings on these two genetically modified mouse models.es
dc.description.filFil: Ahtiainen, Petteri. University of Turku; Finlandia
dc.description.filFil: Rulli, Susana Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina
dc.description.filFil: Pakarainen, Tomi. University of Turku; Finlandia
dc.description.filFil: Zhang, Fu-Ping. University of Helsinki; Finlandia
dc.description.filFil: Poutanen, Matti. University of Turku; Finlandia
dc.description.filFil: Huhtaniemi, Ilpo. University of Turku; Finlandia. Imperial College London; Reino Unido
dc.formatapplication/pdfes
dc.identifier.citationAhtiainen, Petteri; Rulli, Susana Beatriz; Pakarainen, Tomi; Zhang, Fu-Ping; Poutanen, Matti; et al.; Phenotypic characterisation of mice with exaggerated and missing LH/hCG action; Elsevier Ireland; Molecular and Cellular Endocrinology; 260-262; 1-2007; 255-263es
dc.identifier.eissn1872-8057es
dc.identifier.institucionalCONICET
dc.identifier.issn0303-7207es
dc.identifier.repoCONICET Digital
dc.identifier.urihttp://hdl.handle.net/11336/27510
dc.journal.ciudadLimerickes
dc.journal.pagination255-263es
dc.journal.paisIrlandaes
dc.journal.titleMolecular and Cellular Endocrinologyes
dc.journal.volume260-262es
dc.language.isoenges
dc.publisherElsevier Irelandes
dc.relation.alternativeidinfo:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0303720706004357?via%3Dihub#!
dc.relation.alternativeidinfo:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.mce.2005.11.047
dc.relation.alternativeidinfo:eu-repo/semantics/altIdentifier/pmid/17029767
dc.rightsinfo:eu-repo/semantics/openAccess*
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.5/ar/*
dc.subjectHuman Chorionic Gonadotropines
dc.subjectLuteninzing Hormone Receptores
dc.subjectPhenotypees
dc.subjectGene Expressiones
dc.subject.classificationBioquímica y Biología Moleculares
dc.subject.classificationMedicina Básicaes
dc.subject.classificationCIENCIAS MÉDICAS Y DE LA SALUDes
dc.titlePhenotypic characterisation of mice with exaggerated and missing LH/hCG actiones
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:ar-repo/semantics/artículo
dc.typeinfo:eu-repo/semantics/publishedVersion

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