Design of nanostructured lipid carriers and hybrid lipid nanoparticles

Abstract

Nanoparticles composed of solid lipids and their hybrid formulations containing polymers, peptides, proteins, and inorganic compounds are valuable materials for the future development of therapeutic devices. Hybrid lipid carriers are multipurpose, and they can be formulated for the delivery of hydrophobic as well as hydrophilic drugs. Among their main advantages are high payload and stability, established controlled release kinetics, easy targeting, simple production and scale-up, a wide range of administration routes.