Impairment of first-trimester trophoblast cell function by ZIKV infection. Role of VIP in the trophoblast response to the virus.
; Paparini, Daniel Esteban
; Torti, Maria Florencia ; Merech, Fátima Isabel
; Hauk, Vanesa Cintia
; Giovannoni, Federico
; Calo, Guillermina
; Ramhorst, Rosanna Elizabeth
; Garcia, Cybele
; Perez Leiros, Claudia 
Otros responsables
Fecha
2019
Editorial
Elsevier
Revista
Título del libro
Nombre del evento
International Federation of Placenta Association Meeting
Fecha del evento
2019-09-10
Institución organizadora
International Federation of Placenta Association
Latin American Society for Maternal Fetal Interaction and Placenta
Latin American Society for Maternal Fetal Interaction and Placenta
ISSN
0143-4004
eISSN
ISBN
Idioma
Inglés
Tipo del evento
Reunión
Clasificación temática
Palabras clave
Resumen
: Zika virus (ZIKV) infection during pregnancy leads to an increased risk of fetal growth restriction and altered central nervous system development. We have previously demonstrated that the vasoactive intestinal peptide (VIP) favors immune homeostasis maintenance and increases trophoblast cell (Tb) migration at early pregnancy. Our aim is to study the mechanisms of ZIKV infection in first-trimester human Tb cells and the effect of VIP in the Tb response to the virus
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