Robust consistent estimators for ROC curves with covariates

Abstract

The Receiver Operating Characteristic (ROC) curve is a use-ful tool to measure the classification capability of a continuous variable to assess the accuracy of a medical test that distinguishes between two conditions. Sometimes, covariates related to the diagnostic variable may increase the discriminating power of the ROC curve. Due to the lack of stability of classical ROC curves estimators to outliers, we introduce a procedure to obtain robust estimators in presence of covariates. The considered proposal focusses on a semiparametric approach which robustly fits a location-scale regression model to the diagnostic variable and considers robust adaptive empirical estimators of the regression residuals. The uniform consistency of the proposal is derived under mild assumptions. A Monte Carlo study is carried out to compare the performance of the robust proposed estimators with the classical ones both, in clean and contaminated samples. A real data set is also analysed.