Hemodynamic Behaviour During Tilt Test in Patients with Long COVID

Abstract

The Tilt Test is an exam used to assess the cardiovascular autonomic response to postural changes. This study investigated the hemodynamic behavior of patients with Long COVID during the Tilt Test, focusing on changes in systolic (SBP) and diastolic (DBP) blood pressure, in addition to heart rate (HR). The sample consisted of 56 participants, divided into a control group and a study group with a history of COVID-19 infection. The test protocol consisted of 15 min in the supine position, 15 min in the inclined position and, 20 min in the recumbent position. The results showed that patients in the study group had lower blood pressure variability and lower autonomic response compared to the control group, especially in the inclined position. The mean difference of SBP-DBP in the second phase was 35.5 ± 14.0 mmHg in the study group vs 35.7 ± 8.53 mmHg in the control group showing lower hemodynamic adaptation in patients with Long COVID. Such findings may be related to changes in the sensitivity of baroreceptors or reduced venous return. It is concluded that the Tilt Test can be a useful tool to identify autonomic dysfunctions in patients with Long COVID, contributing to the early diagnosis and appropriate clinical management of these individuals.