A novel oxido-vanadium(V) Schiff base complex: Synthesis, spectral characterization, crystal structure, electrochemical evaluation, and biological activity

Abstract

A new oxido-vanadium(V) complex, [VO(L)(PrOH)(OPr)] (L = [(3-methoxy-2oxidobenzylidene)benzohydrazidato], PrOH = propanol, OPr = propanolato) has been synthesized and characterized by means of elemental analysis, Fourier transform infrared (FTIR), proton nuclear magnetic resonance (1HNMR), ultaviolet-visible (UV-Vis) spectroscopy, voltammetry and molar conductivity measurement. The structure of the complex has also determined using single crystal X-ray diffraction. The geometric structure around the V(V) ion has been found to be octahedral in which the positions around the central ion are occupied by ONO ligand donors, oxido groups, and oxygen atoms of coordinated propanol and propoxide group. Electrochemical behavior of this complex is also discussed in more details. In vitro antimicrobial effect of the title complex has investigated exhibiting significant activities against some Gram-positive (Staphylococcus aureus, Micrococcus luteus, Bacillus cereus, Eterococcus faecalis) and Gram-negative bacteria (Pseudomonas aeruginosa, Escherichia coli, Klebsiella sp, Pseudomonas sp) and fungus strain (Candida albicans).