Small-scale metabolic model for lipid production in Rhodosporidium toruloides iTC116

Abstract

This dataset presents the small-scale metabolic model for lipid production by Rhodosporidium toruloides iTC116. The model comprises 93 metabolites, 104 metabolic reactions, and 116 genes, representing key metabolic pathways involved in biomass and lipid production within the extracellular medium, cytosol, and mitochondria compartment. It includes the assimilation of four substrates (glucose, glycerol, xylose, and arabinose), commonly used in biotechnological industries as sole or combined carbon and energy sources. The model also delineates the primary pathways for metabolic precursor, energy, and reducing power, including glycolysis, the pentose phosphate pathway, the tricarboxylic acid cycle, central nitrogen metabolism, oxidative phosphorylation, and the glyoxylate cycle. This resource is designed for use with the COBRA Toolbox for MATLAB and includes a metabolic map for visualizing flux distribution with the Escher pathway map visualization tool.