Electrochemical Sweat Sensors

Abstract

Sweat analysis by means of minimally invasive wearable sensors is considered a potentiallydisruptive method for assessing clinical parameters, with exciting applications in early medicaldiagnostics and high-performance sports. Electrochemical sensors and biosensors are especiallyattractive because of the possibility of the electronic integration of wearable devices. In this article, wereview several aspects regarding the potentialities and present limitations of electrochemical sweat(bio)sensors, including: the main target analytes and their relationships with clinical conditions; mostusual electrochemical techniques of transduction used according to the nature of the target analytes;issues connected to the collection of representative sweat samples; aspects regarding the associated,miniaturized electronic instrumentation used for signal processing and communication; and signalprocessing by machine learning.