The rs1801278 G > A polymorphism of IRS-1 is associated with metabolic syndrome in healthy nondiabetic men. Modulation by cigarette smoking status
; Aranguren, Maria Florencia ; Taverna, Mariano Javier ; Rodríguez, Ricardo G. ; Meroño, Tomás ; Brites, Fernando Daniel ; Poskus, Edgardo ; Frechtel, Gustavo Daniel Otros responsables
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06/2011
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Elsevier Ireland
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Diabetes Research and Clinical Practice
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0168-8227
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Aims: To explore associations between IRS-1 rs1801278 G. > A polymorphism and metabolic syndrome (MS). Methods: rs1801278 G. > A was genotyped in 610 healthy Argentinian men. Results: GA carriers had lower risk of MS (OR = 0.52, P= 0.045), particularly among smokers (OR = 0.10, P= 0.006). Conclusions: rs1801278 GA carriers had lower risk of MS, especially among smokers. © 2011 Elsevier Ireland Ltd.
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Pérez Fernández, María Silvia; Tellechea, Mariana Lorena; Aranguren, Maria Florencia; Taverna, Mariano Javier; Rodríguez, Ricardo G.; et al.; The rs1801278 G > A polymorphism of IRS-1 is associated with metabolic syndrome in healthy nondiabetic men. Modulation by cigarette smoking status; Elsevier Ireland; Diabetes Research and Clinical Practice; 93; 3; 6-2011; e95-e97
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