Immunity and vaccine development efforts against Trypanosoma cruzi | ||
| dc.conicet.fuente | individual | |
| dc.conicet.organizacion | University of Texas Medical Branch | |
| dc.conicet.organizacion | Universidad Autónoma del Estado de México | |
| dc.conicet.organizacion | Universidad Autónoma de Yucatán | |
| dc.conicet.organizacion | Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Salta. Instituto de Patología Experimental. Universidad Nacional de Salta. Facultad de Ciencias de la Salud. Instituto de Patología Experimental | |
| dc.conicet.organizacion | University of Texas Medical Branch | |
| dc.conicet.paisOrganizacion | Estados Unidos | |
| dc.conicet.paisOrganizacion | México | |
| dc.conicet.paisOrganizacion | México | |
| dc.conicet.paisOrganizacion | Argentina | |
| dc.conicet.paisOrganizacion | Estados Unidos | |
| dc.conicet.produccionid | 8368709 | |
| dc.contributor.author | Rios, Lizette E. | |
| dc.contributor.author | Vázquez Chagoyán, Juan Carlos | |
| dc.contributor.author | Pacheco, Antonio Ortega | |
| dc.contributor.author | Zago, María Paola | |
| dc.contributor.author | Garg, Nisha J. | |
| dc.date.accessioned | 2020-10-27T20:56:07Z | |
| dc.date.available | 2020-10-27T20:56:07Z | |
| dc.date.issued | 2019-12 | |
| dc.date.updated | 2020-05-19T19:45:07Z | |
| dc.description.abstract | Trypanosoma cruzi (T. cruzi) is the causative agent for Chagas disease (CD). There is a critical lack of methods for prevention of infection or treatment of acute infection and chronic disease. Studies in experimental models have suggested that the protective immunity against T. cruzi infection requires the elicitation of Th1 cytokines, lytic antibodies and the concerted activities of macrophages, T helper cells, and cytotoxic T lymphocytes (CTLs). In this review, we summarize the research efforts in vaccine development to date and the challenges faced in achieving an efficient prophylactic or therapeutic vaccine against human CD. | es |
| dc.description.fil | Fil: Rios, Lizette E.. University of Texas Medical Branch; Estados Unidos | |
| dc.description.fil | Fil: Vázquez Chagoyán, Juan Carlos. Universidad Autónoma del Estado de México; México | |
| dc.description.fil | Fil: Pacheco, Antonio Ortega. Universidad Autónoma de Yucatán; México | |
| dc.description.fil | Fil: Zago, María Paola. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Salta. Instituto de Patología Experimental. Universidad Nacional de Salta. Facultad de Ciencias de la Salud. Instituto de Patología Experimental; Argentina | |
| dc.description.fil | Fil: Garg, Nisha J.. University of Texas Medical Branch; Estados Unidos | |
| dc.format | application/pdf | es |
| dc.identifier.citation | Rios, Lizette E.; Vázquez Chagoyán, Juan Carlos; Pacheco, Antonio Ortega; Zago, María Paola; Garg, Nisha J.; Immunity and vaccine development efforts against Trypanosoma cruzi; Elsevier Science; Acta Tropica; 200; 105168; 12-2019; 1-11 | es |
| dc.identifier.institucional | CONICET | |
| dc.identifier.issn | 0001-706X | es |
| dc.identifier.repo | CONICET Digital | |
| dc.identifier.uri | http://hdl.handle.net/11336/116983 | |
| dc.journal.number | 105168 | es |
| dc.journal.pagination | 1-11 | es |
| dc.journal.pais | Países Bajos | es |
| dc.journal.title | Acta Tropica | es |
| dc.journal.volume | 200 | es |
| dc.language.iso | eng | es |
| dc.publisher | Elsevier Science | es |
| dc.relation.alternativeid | info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.actatropica.2019.105168 | |
| dc.relation.alternativeid | info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0001706X19303572 | |
| dc.rights | info:eu-repo/semantics/openAccess | * |
| dc.rights.uri | https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ | * |
| dc.subject | ADJUVANTS | es |
| dc.subject | CHAGAS | es |
| dc.subject | IMMUNITY | es |
| dc.subject | PROPHYLACTIC | es |
| dc.subject | THERAPEUTIC | es |
| dc.subject | VACCINE | es |
| dc.subject.classification | Parasitología | es |
| dc.subject.classification | Ciencias de la Salud | es |
| dc.subject.classification | CIENCIAS MÉDICAS Y DE LA SALUD | es |
| dc.title | Immunity and vaccine development efforts against Trypanosoma cruzi | es |
| dc.type | info:eu-repo/semantics/article | |
| dc.type | info:ar-repo/semantics/artículo | |
| dc.type | info:eu-repo/semantics/publishedVersion | |
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