Platelet TLR4 at the crossroads of thrombosis and the innate immune response

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dc.conicet.fuenteCrossref
dc.conicet.organizacionConsejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Medicina Experimental. Academia Nacional de Medicina de Buenos Aires. Instituto de Medicina Experimental
dc.conicet.paisOrganizacionArgentina
dc.conicet.produccionid8767779
dc.contributor.authorSchattner, Mirta Ana
dc.date.accessioned2021-03-09T21:09:48Z
dc.date.available2021-03-09T21:09:48Z
dc.date.issued2018-12-04
dc.date.updated2020-12-22T15:46:45Z
dc.description.abstractPlatelet TLR-4 activation by pathogen- or damage-associated molecular pattern molecules triggers pro-thrombotic, proinflammatory, and pro-coagulant effector responses. Moreover, platelet TLR4 has a prominent role as a sensor of high lipopolysaccharide circulating levels during sepsis and in the clearance of pathogens mediated by neutrophils. This review presents evidence pointing to TLR4 as a bridge connecting thrombosis and innate immunity.es
dc.description.filFil: Schattner, Mirta Ana. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Medicina Experimental. Academia Nacional de Medicina de Buenos Aires. Instituto de Medicina Experimental; Argentina
dc.formatapplication/pdfes
dc.identifier.citationSchattner, Mirta Ana; Platelet TLR4 at the crossroads of thrombosis and the innate immune response; Federation of American Societies for Experimental Biology; Journal of Leukocyte Biology; 105; 5; 4-12-2018; 873-880es
dc.identifier.institucionalCONICET
dc.identifier.issn0741-5400es
dc.identifier.repoCONICET Digital
dc.identifier.urihttp://hdl.handle.net/11336/127868
dc.journal.ciudadBethesdaes
dc.journal.number5es
dc.journal.pagination873-880es
dc.journal.paisEstados Unidoses
dc.journal.titleJournal of Leukocyte Biologyes
dc.journal.volume105es
dc.language.isoenges
dc.publisherFederation of American Societies for Experimental Biologyes
dc.relation.alternativeidinfo:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/abs/10.1002/JLB.MR0618-213R
dc.relation.alternativeidinfo:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1002/JLB.MR0618-213R
dc.relation.isreferencedininfo:eu-repo/semantics/reference/url/http://dx.doi.org/10.1002/ajh.24097
dc.rightsinfo:eu-repo/semantics/openAccess*
dc.rights.urihttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/*
dc.subjectHMGB-1es
dc.subjectLPSes
dc.subjectNETSes
dc.subjectPLATELETSes
dc.subjectSEPSISes
dc.subjectTHROMBOSISes
dc.subjectTLRSes
dc.subject.classificationBioquímica y Biología Moleculares
dc.subject.classificationCiencias Biológicases
dc.subject.classificationCIENCIAS NATURALES Y EXACTASes
dc.titlePlatelet TLR4 at the crossroads of thrombosis and the innate immune responsees
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:ar-repo/semantics/artículo
dc.typeinfo:eu-repo/semantics/publishedVersion

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