Uptake of ivermectin from growing substrate to plant species

Abstract

Ivermectin (IVM) is a worldwide-used antiparasitic drug. However, its high level of faecal elimination together with its transfer from dung pats to the underlying soil as well as the common practice of using manure for soil amendement represents a potencial risk to plants growing in these substrates. Two trials were conducted to evaluate the uptake of IVM to: 1) a crop of ryegrass (Lolium multiflorum) and clover (Trifolium repens) growing for 120 days post treatment (dpt) in IVM-spiked soil at 3000 (High group, HG) and 90ng/g (Low group, LG); and 2) a crop of radish (Raphanus sativus) and lettuce (Lactuca sativa) growing for 60 dpt in a mix of soil and 10% IVM-spiked manure at 3000ng/g. Soil, soil-manure mix and plants were sampled starting at 15 dpt and at the end of each trial. All matrices were analyzed by HPLC to quantify IVM concentration. Trial 1: In HG, IVM concentration in soil decreased Ivermectin (IVM) is a worldwide-used antiparasitic drug. However, its high level of faecal elimination together with its transfer from dung pats to the underlying soil as well as the common practice of using manure for soil amendement represents a potencial risk to plants growing in these substrates. Two trials were conducted to evaluate the uptake of IVM to: 1) a crop of ryegrass (Lolium multiflorum) and clover (Trifolium repens) growing for 120 days post treatment (dpt) in IVM-spiked soil at 3000 (High group, HG) and 90ng/g (Low group, LG); and 2) a crop of radish (Raphanus sativus) and lettuce (Lactuca sativa) growing for 60 dpt in a mix of soil and 10% IVM-spiked manure at 3000ng/g. Soil, soil-manure mix and plants were sampled starting at 15 dpt and at the end of each trial. All matrices were analyzed by HPLC to quantify IVM concentration. Trial 1: In HG, IVM concentration in soil decreased.