Distinct Mechanisms of Dissemination of NDM-1 Metallo-β-Lactamase in Acinetobacter Species in Argentina
; Martinez, Jasmine ; Huang, Fanny ; Liu, Christine ; Fernandez, Jennifer ; López, María Carolina ; Gonzalez, Lisandro Javier ; Albornoz, Ezequiel Pablo ; Corso, Alejandra ; Vila, Alejandro Jose ; Bonomo, Robert A. ; Ramirez, Maria Soledad Otros responsables
Fecha
04/2020
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American Society for Microbiology
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Antimicrobial Agents and Chemotherapy
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0066-4804
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A 4-year surveillance of carbapenem-resistant Acinetobacter spp. isolates in Argentina identified 40 strains carrying blaNDM-1. Genome sequencing revealed that most were Acinetobacter baumannii, whereas seven represented other Acinetobacter spp. The A. baumannii genomes were closely related, suggesting recent spread. blaNDM-1 was located in the chromosome of A. baumannii strains and on a plasmid in non-A. baumannii strains. A resistance gene island carrying blaPER-7 and other resistance determinants was found on a plasmid in some A. baumannii strains.
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Adams, Mark D.; Pasteran, Fernando; Traglia, German Matias; Martinez, Jasmine; Huang, Fanny; et al.; Distinct Mechanisms of Dissemination of NDM-1 Metallo-β-Lactamase in Acinetobacter Species in Argentina; American Society for Microbiology; Antimicrobial Agents and Chemotherapy; 64; 5; 4-2020; 1-13
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