Regulation of lipid peroxidation and ferroptosis in diverse species | ||
| dc.conicet.fuente | individual | |
| dc.conicet.organizacion | Helmholtz Center Munich German Research Center For Environmental Health | |
| dc.conicet.organizacion | University of Pittsburgh at Johnstown | |
| dc.conicet.organizacion | University of Pittsburgh | |
| dc.conicet.organizacion | Sechenov First Moscow State Medical University | |
| dc.conicet.organizacion | University of Pittsburgh | |
| dc.conicet.organizacion | University of Pittsburgh at Johnstown | |
| dc.conicet.organizacion | Universidad Nacional de Mar del Plata | |
| dc.conicet.organizacion | Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones Biológicas. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales. Instituto de Investigaciones Biológicas | |
| dc.conicet.organizacion | Linus Pauling Institute | |
| dc.conicet.organizacion | State University of Oregon | |
| dc.conicet.organizacion | Linus Pauling Institute | |
| dc.conicet.organizacion | State University of Oregon | |
| dc.conicet.organizacion | Columbia University | |
| dc.conicet.paisOrganizacion | ||
| dc.conicet.paisOrganizacion | Estados Unidos | |
| dc.conicet.paisOrganizacion | Estados Unidos | |
| dc.conicet.paisOrganizacion | ||
| dc.conicet.paisOrganizacion | Estados Unidos | |
| dc.conicet.paisOrganizacion | Estados Unidos | |
| dc.conicet.paisOrganizacion | Argentina | |
| dc.conicet.paisOrganizacion | Argentina | |
| dc.conicet.paisOrganizacion | ||
| dc.conicet.paisOrganizacion | Estados Unidos | |
| dc.conicet.paisOrganizacion | ||
| dc.conicet.paisOrganizacion | Estados Unidos | |
| dc.conicet.paisOrganizacion | Estados Unidos | |
| dc.conicet.produccionid | 8067002 | |
| dc.contributor.author | Conrad, Marcus | |
| dc.contributor.author | Kagan, Valerian E. | |
| dc.contributor.author | Bayir, Hülya | |
| dc.contributor.author | Pagnussat, Gabriela Carolina | |
| dc.contributor.author | Head, Brian | |
| dc.contributor.author | Traber, Maret G. | |
| dc.contributor.author | Stockwell, Brent R. | |
| dc.date.accessioned | 2019-10-29T18:10:16Z | |
| dc.date.available | 2019-10-29T18:10:16Z | |
| dc.date.issued | 2018-05 | |
| dc.date.updated | 2019-10-22T15:54:05Z | |
| dc.description.abstract | Lipid peroxidation is the process by which oxygen combines with lipids to generate lipid hydroperoxides via intermediate formation of peroxyl radicals. Vitamin E and coenzyme Q10 react with peroxyl radicals to yield peroxides, and then these oxidized lipid species can be detoxified by glutathione and glutathione peroxidase 4 (GPX4) and other components of the cellular antioxidant defense network. Ferroptosis is a form of regulated nonapoptotic cell death involving overwhelming iron-dependent lipid peroxidation. Here, we review the functions and regulation of lipid peroxidation, ferroptosis, and the antioxidant network in diverse species, including humans, other mammals and vertebrates, plants, invertebrates, yeast, bacteria, and archaea. We also discuss the potential evolutionary roles of lipid peroxidation and ferroptosis. | es |
| dc.description.fil | Fil: Conrad, Marcus. Helmholtz Center Munich German Research Center For Environmental Health; | |
| dc.description.fil | Fil: Kagan, Valerian E.. University of Pittsburgh at Johnstown; Estados Unidos. University of Pittsburgh; Estados Unidos. Sechenov First Moscow State Medical University; | |
| dc.description.fil | Fil: Bayir, Hülya. University of Pittsburgh; Estados Unidos. University of Pittsburgh at Johnstown; Estados Unidos | |
| dc.description.fil | Fil: Pagnussat, Gabriela Carolina. Universidad Nacional de Mar del Plata; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones Biológicas. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales. Instituto de Investigaciones Biológicas; Argentina | |
| dc.description.fil | Fil: Head, Brian. Linus Pauling Institute; . State University of Oregon; Estados Unidos | |
| dc.description.fil | Fil: Traber, Maret G.. Linus Pauling Institute; . State University of Oregon; Estados Unidos | |
| dc.description.fil | Fil: Stockwell, Brent R.. Columbia University; Estados Unidos | |
| dc.format | application/pdf | es |
| dc.identifier.citation | Conrad, Marcus; Kagan, Valerian E.; Bayir, Hülya; Pagnussat, Gabriela Carolina; Head, Brian; et al.; Regulation of lipid peroxidation and ferroptosis in diverse species; Cold Spring Harbor Laboratory Press; Genes & Development.; 32; 9-10; 5-2018; 602-619 | es |
| dc.identifier.institucional | CONICET | |
| dc.identifier.issn | 0890-9369 | es |
| dc.identifier.repo | CONICET Digital | |
| dc.identifier.uri | http://hdl.handle.net/11336/87563 | |
| dc.journal.number | 9-10 | es |
| dc.journal.pagination | 602-619 | es |
| dc.journal.pais | Estados Unidos | es |
| dc.journal.title | Genes & Development. | es |
| dc.journal.volume | 32 | es |
| dc.language.iso | eng | es |
| dc.publisher | Cold Spring Harbor Laboratory Press | es |
| dc.relation.alternativeid | info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1101/gad.314674.118 | |
| dc.relation.alternativeid | info:eu-repo/semantics/altIdentifier/url/http://genesdev.cshlp.org/content/32/9-10/602 | |
| dc.rights | info:eu-repo/semantics/openAccess | * |
| dc.rights.uri | https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ | * |
| dc.subject | CELL DEATH | es |
| dc.subject | FERROPTOSIS | es |
| dc.subject | IRON | es |
| dc.subject | LIPID PEROXIDATION | es |
| dc.subject | ROS | es |
| dc.subject | VITAMIN E | es |
| dc.subject.classification | Bioquímica y Biología Molecular | es |
| dc.subject.classification | Ciencias Biológicas | es |
| dc.subject.classification | CIENCIAS NATURALES Y EXACTAS | es |
| dc.title | Regulation of lipid peroxidation and ferroptosis in diverse species | es |
| dc.type | info:eu-repo/semantics/article | |
| dc.type | info:ar-repo/semantics/artículo | |
| dc.type | info:eu-repo/semantics/publishedVersion | |
Archivos
Bloque original
Cargando...
- Nombre:
- CONICET_Digital_Nro.25ac7db3-cc76-4919-979d-e27609bc51ce_A.pdf
- Tamaño:
- 1.74 MB
- Formato:
- Adobe Portable Document Format