Lipid peroxidation modifies the assembly of biological membranes "The lipid Whisker Model"

Abstract

The aim of this opinion article is to point out the basic principles that modify the assembly of biological membranes during lipid peroxidation. With this objective in mind I describe: the structural and functional properties of membranes, the transport and diffusion of oxygen regulated by cholesterol and fatty acids; the "Lipid Whisker Model" and finally I analyze the changes induced by lipid peroxidation in membrane structure and dynamics, both at the lipid and protein level.