Effect of background melanopsin activation levels on contrast sensitivity mediated by postreceptoral pathways

Abstract

Intrinsically photosensitive retinal ganglion cells (ipRGCs) are sensitive to light through a photopigment called melanopsin. IpRGCs project axons to the lateral geniculate nucleus, suggesting melanopsin activation may contribute to visual perception. Here, we assessed the effect of background melanopsin activation level on contrast sensitivity mediated by the magno- (MC-), parvo- (PC-) and konio-cellular (KC-) pathways.