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dc.contributor.author
Oliva, María de los Ángeles  
dc.contributor.author
Sombra, Lorena Luján  
dc.contributor.author
Olsina, Roberto Antonio  
dc.contributor.author
Masi, Adriana Noemi  
dc.date.available
2020-02-18T20:42:58Z  
dc.date.issued
2005-09  
dc.identifier.citation
Oliva, María de los Ángeles; Sombra, Lorena Luján; Olsina, Roberto Antonio; Masi, Adriana Noemi; A new fluorescent assay for enalapril maleate; Springer/Plenum Publishers; Journal Of Fluorescence; 15; 5; 9-2005; 723-728  
dc.identifier.issn
1053-0509  
dc.identifier.uri
http://hdl.handle.net/11336/97983  
dc.description.abstract
A new spectrofluorimetric method for the enalapril maleate monitoring was studied. Enalapril maleate was found to be highly photolabile. This drug was evaluated according to photodegradation assay at pH 2.5 and 6. Enalapril maleate was exposed to UVA-UVB radiations. Under these specific conditions was found as degradation product, the diketopiperazine. The modification of the fluorescent properties of enalapril maleate in solution after exposure UV-radiation and the degradation mechanisms were studied. The photodegradation was followed by the developed spectrofluorimetric assay.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Springer/Plenum Publishers  
dc.rights
info:eu-repo/semantics/restrictedAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
DIKETOPIPERAZINE  
dc.subject
ENALAPRIL MALEATE  
dc.subject
FLUORESCENCE  
dc.subject
PHOTODEGRADATION  
dc.subject.classification
Química Analítica  
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Ciencias Químicas  
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CIENCIAS NATURALES Y EXACTAS  
dc.title
A new fluorescent assay for enalapril maleate  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2020-02-13T20:03:44Z  
dc.journal.volume
15  
dc.journal.number
5  
dc.journal.pagination
723-728  
dc.journal.pais
Estados Unidos  
dc.journal.ciudad
Nueva York  
dc.description.fil
Fil: Oliva, María de los Ángeles. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina  
dc.description.fil
Fil: Sombra, Lorena Luján. Universidad Nacional de San Luis; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina  
dc.description.fil
Fil: Olsina, Roberto Antonio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; Argentina  
dc.description.fil
Fil: Masi, Adriana Noemi. Universidad Nacional de San Luis; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina  
dc.journal.title
Journal Of Fluorescence  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1007/s10895-005-2979-3  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://dx.doi.org/10.1007/s10895-005-2979-3  

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