Artículo

A new fluorescent assay for enalapril maleate

Oliva, María de los Ángeles; Sombra, Lorena LujánIcon ; Olsina, Roberto AntonioIcon ; Masi, Adriana NoemiIcon
Fecha de publicación: 09/2005
Editorial: Springer/Plenum Publishers
Revista: Journal Of Fluorescence
ISSN: 1053-0509
Idioma: Inglés
Tipo de recurso: Artículo publicado
Clasificación temática:

Resumen

A new spectrofluorimetric method for the enalapril maleate monitoring was studied. Enalapril maleate was found to be highly photolabile. This drug was evaluated according to photodegradation assay at pH 2.5 and 6. Enalapril maleate was exposed to UVA-UVB radiations. Under these specific conditions was found as degradation product, the diketopiperazine. The modification of the fluorescent properties of enalapril maleate in solution after exposure UV-radiation and the degradation mechanisms were studied. The photodegradation was followed by the developed spectrofluorimetric assay.
Palabras clave: DIKETOPIPERAZINE , ENALAPRIL MALEATE , FLUORESCENCE , PHOTODEGRADATION
 
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info:eu-repo/semantics/restrictedAccess Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution-NonCommercial-ShareAlike 2.5 Unported (CC BY-NC-SA 2.5)
Identificadores
URI: http://hdl.handle.net/11336/97983
DOI: http://dx.doi.org/10.1007/s10895-005-2979-3
URL: http://dx.doi.org/10.1007/s10895-005-2979-3
Colecciones
Articulos(INQUISAL)
Articulos de INST. DE QUIMICA DE SAN LUIS
Citación
Oliva, María de los Ángeles; Sombra, Lorena Luján; Olsina, Roberto Antonio; Masi, Adriana Noemi; A new fluorescent assay for enalapril maleate; Springer/Plenum Publishers; Journal Of Fluorescence; 15; 5; 9-2005; 723-728
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