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dc.contributor.author
Margarit, David Hipólito  
dc.contributor.author
Romanelli, Lilia Mabel  
dc.contributor.author
Fendrik, Alejandro José  
dc.date.available
2020-02-13T14:03:49Z  
dc.date.issued
2018-04  
dc.identifier.citation
Margarit, David Hipólito; Romanelli, Lilia Mabel; Fendrik, Alejandro José; A 3D Cellular Automaton for Cell Differentiation in a Solid Tumor with Plasticity; World Scientific; Biophysical Reviews and Letters; 13; 01; 4-2018; 19-28  
dc.identifier.issn
1793-7035  
dc.identifier.uri
http://hdl.handle.net/11336/97379  
dc.description.abstract
A model with spherical symmetry is proposed. We analyze the appropriate parameters of cell dierentiation for different kinds of cells (Cancer Stem Cells (CSC) and Differentiated Cells(DC)). The plasticity (capacity to return from a DC to its previous state of CSC) is taken intoaccount. Following this hypothesis, the dissemination of CSCs to another organ is analyzed. The location of the cells in the tumor and the plasticity range for possible metastasis is discussed.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
World Scientific  
dc.rights
info:eu-repo/semantics/openAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
Celular automaton  
dc.subject
Cell differentiation  
dc.subject
Cancer stem cells  
dc.subject
Plasticity  
dc.subject.classification
Otras Ciencias Físicas  
dc.subject.classification
Ciencias Físicas  
dc.subject.classification
CIENCIAS NATURALES Y EXACTAS  
dc.title
A 3D Cellular Automaton for Cell Differentiation in a Solid Tumor with Plasticity  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2019-12-20T22:53:49Z  
dc.journal.volume
13  
dc.journal.number
01  
dc.journal.pagination
19-28  
dc.journal.pais
Singapur  
dc.description.fil
Fil: Margarit, David Hipólito. Universidad Nacional de General Sarmiento. Instituto de Ciencias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina  
dc.description.fil
Fil: Romanelli, Lilia Mabel. Universidad Nacional de General Sarmiento. Instituto de Ciencias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina  
dc.description.fil
Fil: Fendrik, Alejandro José. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de General Sarmiento. Instituto de Ciencias; Argentina  
dc.journal.title
Biophysical Reviews and Letters  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.worldscientific.com/doi/abs/10.1142/S1793048018500029  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/https://doi.org/10.1142/S1793048018500029  

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