Artículo
Feasibility of dose enhancement assessment: Preliminary results by means of Gd-infused polymer gel dosimeter and Monte Carlo study
Fecha de publicación:
11/11/2018
Editorial:
Pergamon-Elsevier Science Ltd
Revista:
Applied Radiation and Isotopes
ISSN:
0969-8043
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
This work reports the experimental development of an integral Gd-infused dosimeter suitable for Gd dose enhancement assessment along with Monte Carlo simulations applied to determine the dose enhancement by radioactive and X-ray sources of interest in conventional and electronic brachytherapy. In this context, capability to elaborate a stable and reliable Gd-infused dosimeter was the first goal aimed at direct and accurate measurements of dose enhancement due to Gd presence. Dose-response was characterized for standard and Gd-infused PAGAT polymer gel dosimeters by means of optical transmission/absorbance. The developed Gd-infused PAGAT dosimeters demonstrated to be stable presenting similar dose-response as standard PAGAT within a linear trend up to 13 Gy along with good post-irradiation readout stability verified at 24 and 48 h. Additionally, dose enhancement was evaluated for Gd-infused PAGAT dosimeters by means of Monte Carlo (PENELOPE) simulations considering scenarios for isotopic and X-ray generator sources. The obtained results demonstrated the feasibility of obtaining a maximum enhancement around of (14 ± 1)% for 192 Ir source and an average enhancement of (70 ± 13)% for 241 Am. However, dose enhancement up to (267 ± 18)% may be achieved if suitable filtering is added to the 241 Am source. On the other hand, optimized X-ray spectra may attain dose enhancements up to (253 ± 22) %, which constitutes a promising future alternative for replacing radioactive sources by implementing electronic brachytherapy achieving high dose levels.
Palabras clave:
ELECTRONIC BRACHYTHERAPY
,
GD DOSE ENHANCEMENT
,
PAGAT GEL DOSIMETRY
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Articulos(IFEG)
Articulos de INST.DE FISICA ENRIQUE GAVIOLA
Articulos de INST.DE FISICA ENRIQUE GAVIOLA
Citación
Santibáñez, M.; Guillen, Y.; Chacón Obando, David; Figueroa, R.G.; Valente, Mauro Andres; Feasibility of dose enhancement assessment: Preliminary results by means of Gd-infused polymer gel dosimeter and Monte Carlo study; Pergamon-Elsevier Science Ltd; Applied Radiation and Isotopes; 141; 11-11-2018; 210-218
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