Artículo
First clinical isolation of an azole-resistant aspergillus fumigatus isolate harboring a TR46 Y121F T289A mutation in South America
Isla, Guillermina; Leonardelli, Florencia
; Tiraboschi, Iris Nora; Refojo, Nicolás; Hevia, Alejandra; Vivot, Walter Oscar; Szusz, Wanda; Córdoba, Susana Beatríz; García Effron, Guillermo
; Tiraboschi, Iris Nora; Refojo, Nicolás; Hevia, Alejandra; Vivot, Walter Oscar; Szusz, Wanda; Córdoba, Susana Beatríz; García Effron, Guillermo
Fecha de publicación:
10/2018
Editorial:
American Society for Microbiology
Revista:
Antimicrobial Agents and Chemotherapy
ISSN:
0066-4804
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
One of the most recently described Aspergillus fumigatus CYP51Amediated azole resistance mechanisms is TR46 Y121F T289A. Clinical A. fumigatus strains harboring these substitutions have been reported worldwide, with the exception of South America. We describe the first clinical A. fumigatus strain with this resistance mechanism isolated from an Argentinian patient. The strain was isolated in 2009 (1 year after the first-described mutant in United States), demonstrating that these alleles were scattered worldwide earlier than previously thought.
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Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción:
Creative Commons Attribution-NonCommercial-ShareAlike 2.5 Unported (CC BY-NC-SA 2.5)
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Colecciones
Articulos(CCT - SANTA FE)
Articulos de CTRO.CIENTIFICO TECNOL.CONICET - SANTA FE
Articulos de CTRO.CIENTIFICO TECNOL.CONICET - SANTA FE
Citación
Isla, Guillermina; Leonardelli, Florencia; Tiraboschi, Iris Nora; Refojo, Nicolás; Hevia, Alejandra; et al.; First clinical isolation of an azole-resistant aspergillus fumigatus isolate harboring a TR46 Y121F T289A mutation in South America; American Society for Microbiology; Antimicrobial Agents and Chemotherapy; 62; 10; 10-2018; 1-7
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