Artículo

Total Synthesis of Waltherione F, a Nonrutaceous 3-Methoxy-4-quinolone, Isolated from Waltheria indica L. F.

Arroyo Aguilar, Abel AlfredoIcon ; Bolivar Avila, Santiago JuniorIcon ; Kaufman, Teodoro SaulIcon ; Larghi, Enrique LeandroIcon
Fecha de publicación: 08/2018
Editorial: American Chemical Society
Revista: Organic Letters
ISSN: 1523-7060
Idioma: Inglés
Tipo de recurso: Artículo publicado
Clasificación temática:

Resumen

Waltherione F was totally synthesized in seven steps and 31% overall yield from 2-nitro-3-methylanisole without the use of protecting groups. Key steps in the sequence were a Suzuki-Miyaura coupling to attach the n-octyl chain and a microwave-promoted cyclization of an acetonyl anthranilate to give the heterocyclic core whose 3-OH was O-methylated.
Palabras clave: Natural Product , Organic Synthesis , Walterione A
 
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info:eu-repo/semantics/openAccess Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution-NonCommercial-ShareAlike 2.5 Unported (CC BY-NC-SA 2.5)
Identificadores
URI: http://hdl.handle.net/11336/86761
DOI: http://dx.doi.org/10.1021/acs.orglett.8b02221
URL: https://pubs.acs.org/doi/10.1021/acs.orglett.8b02221
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Articulos(IQUIR)
Articulos de INST.DE QUIMICA ROSARIO
Citación
Arroyo Aguilar, Abel Alfredo; Bolivar Avila, Santiago Junior; Kaufman, Teodoro Saul; Larghi, Enrique Leandro; Total Synthesis of Waltherione F, a Nonrutaceous 3-Methoxy-4-quinolone, Isolated from Waltheria indica L. F.; American Chemical Society; Organic Letters; 20; 16; 8-2018; 5058-5061
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