Evaluation of the polyphenolic content, anti-inflammatory and antioxidant activities of total extract from eugenia pyriformes cambess (uvaia) fruits

Abstract

Eugenia pyriformes Cambess is a plant native to Brazil, where it is known as "uvaia." Their fruits are used in juice or are eaten raw. In this study, fruits from nine different genotypes were investigated for their in vitro antichemotactic activity, their antioxidant activity and their total polyphenolic content. The extract showed similar antichemotactic and antioxidant activities and had substantially different total polyphenolic contents. The samples were also investigated for antiedematogenic and antioxidant activity in animal models. The total extract of uvaia exhibited significant dose-related anti-inflammatory and antioxidant activity at 0.5 and 1.0 g/kg b.w.