A new inorganic photolabile protecting group for highly efficient visible light GABA uncaging

Inhibiting with visible light. An inorganic‐based caged compound of the inhibitory neurotransmitter, γ‐amino butyric acid (GABA), was prepared and photolysed by light at 450 nm with the highest uncaging quantum yield reported to date. GABA ion channels were activated by irradiation in a biological preparation by using this caged compound. (Image courtesy of the CNS Forum http://www.cnsforum.com)

Palabras clave: Cage Compounds , Gaba , Gamma-Aminobutyric Acid , Photolysis , Ruthenium

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Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution-NonCommercial-ShareAlike 2.5 Unported (CC BY-NC-SA 2.5)

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URI: http://hdl.handle.net/11336/79692

DOI: http://dx.doi.org/10.1002/cbic.200700354

URL: https://onlinelibrary.wiley.com/doi/abs/10.1002/cbic.200700354

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Articulos(INGEBI)
Articulos de INST.DE INVEST.EN ING.GENETICA Y BIOL.MOLECULAR "DR. HECTOR N TORRES"

Citación

Zayat, Leonardo Martin; Noval, María Gabriela; Campi, Julieta; Calero, Cecilia Ines; Calvo, Daniel Juan; et al.; A new inorganic photolabile protecting group for highly efficient visible light GABA uncaging; Wiley VCH Verlag; Chembiochem; 8; 17; 11-2007; 2035-2038

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