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dc.contributor.author
Arruvito, Maria Lourdes  
dc.contributor.author
Fainboim, Leonardo  
dc.date.available
2019-01-07T20:20:38Z  
dc.date.issued
2011-03  
dc.identifier.citation
Arruvito, Maria Lourdes; Fainboim, Leonardo; Mechanisms involved in the expansion of Tregs during pregnancy: Role of IL-2/STAT5 signalling; Elsevier Ireland; Journal of Reproductive Immunology; 88; 2; 3-2011; 93-98  
dc.identifier.issn
0165-0378  
dc.identifier.uri
http://hdl.handle.net/11336/67626  
dc.description.abstract
Several studies have reported that the fine-tuning of regulatory T cells (Tregs) is required for a successful pregnancy and for the control of autoimmune diseases. Here, we review the mechanisms that control the expansion of Tregs, based on insights obtained from the study of women suffering unsuccessful pregnancies and on recent data from patients with autoimmune diseases or with chronic viral infections such as HCV. In particular, we review the role of endocrine factors and IL-2/STAT5 signalling in the impaired expansion of Tregs.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Elsevier Ireland  
dc.rights
info:eu-repo/semantics/openAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
Human Reproduction  
dc.subject
Il-2  
dc.subject
Regulatory T Cell  
dc.subject
Stat-5  
dc.subject.classification
Inmunología  
dc.subject.classification
Medicina Básica  
dc.subject.classification
CIENCIAS MÉDICAS Y DE LA SALUD  
dc.title
Mechanisms involved in the expansion of Tregs during pregnancy: Role of IL-2/STAT5 signalling  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2019-01-07T13:32:03Z  
dc.journal.volume
88  
dc.journal.number
2  
dc.journal.pagination
93-98  
dc.journal.pais
Irlanda  
dc.journal.ciudad
Shannon  
dc.description.fil
Fil: Arruvito, Maria Lourdes. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Inmunología, Genética y Metabolismo. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Inmunología, Genética y Metabolismo; Argentina. Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas General San Martín; Argentina  
dc.description.fil
Fil: Fainboim, Leonardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Inmunología, Genética y Metabolismo. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Inmunología, Genética y Metabolismo; Argentina. Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas General San Martín; Argentina  
dc.journal.title
Journal of Reproductive Immunology  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/https://doi.org/10.1016/j.jri.2010.12.007  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0165037811000064