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dc.contributor.author
Brouard, Danny
dc.contributor.author
Viger, Mathieu L.
dc.contributor.author
Bracamonte, Angel Guillermo
dc.contributor.author
Boudreau, Denis
dc.date.available
2018-12-28T12:57:48Z
dc.date.issued
2011-03
dc.identifier.citation
Brouard, Danny; Viger, Mathieu L.; Bracamonte, Angel Guillermo; Boudreau, Denis; Label-free biosensing based on multilayer fluorescent nanocomposites and a cationic polymeric transducer; American Chemical Society; ACS Nano; 5; 3; 3-2011; 1888-1896
dc.identifier.issn
1936-0851
dc.identifier.uri
http://hdl.handle.net/11336/67128
dc.description.abstract
This study describes the preparation and characterization of a DNA sensing architecture combining the molecular recognition capabilities of a cationic conjugated polymer transducer with highly fluorescent core-shell nanoparticles (NPs). The very structure of the probe-labeled NPs and the polymer-induced formation of NP aggregates maximize the proximity between the polymer donor and acceptor NPs that is required for optimal resonant energy transfer. Each hybridization event is signaled by a potentially large number of excited reporters following the efficient plasmon-enhanced energy transfer between target-activated polymer transducer and fluorophores located in the self-assembled core-shell aggregates, resulting in direct molecular detection of target nucleic acids at femtomolar concentrations. © 2011 American Chemical Society.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
American Chemical Society
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Dna Sensing
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Fluorescence Enhancement
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Plasmonic
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Resonant Energy Transfer
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Silver Core-Silica Shell Nanoparticles
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Otras Ciencias Químicas
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Ciencias Químicas
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CIENCIAS NATURALES Y EXACTAS
dc.title
Label-free biosensing based on multilayer fluorescent nanocomposites and a cationic polymeric transducer
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2018-11-22T15:29:38Z
dc.journal.volume
5
dc.journal.number
3
dc.journal.pagination
1888-1896
dc.journal.pais
Estados Unidos
dc.journal.ciudad
Washington
dc.description.fil
Fil: Brouard, Danny. Laval University; Canadá
dc.description.fil
Fil: Viger, Mathieu L.. Laval University; Canadá
dc.description.fil
Fil: Bracamonte, Angel Guillermo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Laval University; Canadá
dc.description.fil
Fil: Boudreau, Denis. Laval University; Canadá
dc.journal.title
ACS Nano
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1021/nn102776m
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://pubs.acs.org/doi/abs/10.1021/nn102776m
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