Artículo
Multiple response optimization of heat shock process for separation of bovine serum albumin from plasma
Fecha de publicación:
08/2017
Editorial:
Taylor
Revista:
Separation Science and Technology
ISSN:
0149-6395
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
Bovine serum albumin produced by heat shock from bovine plasma has been researched for the effects of sodium caprylate concentration [Cap], temperature (T), and pH on yield (Yield%) and purity (BSA%). Response surface methodology and desirability function approaches were applied to optimize its process. The best compromise solution was found with BSA% = 95.0 and Yield% = 28.5 for a [Cap] = 2 mM, T = 67.9°C, and pH = 5. A Monte Carlo simulation showed that it is possible to obtain excellent values for each individual response. However, a techno-economic feasibility study must be carried out to determine which one is the best option.
Archivos asociados
Licencia
Identificadores
Colecciones
Articulos(INTEQUI)
Articulos de INST. DE INVEST. EN TECNOLOGIA QUIMICA
Articulos de INST. DE INVEST. EN TECNOLOGIA QUIMICA
Citación
Gonzalez, Ulises Andres; Menendez, C.; Saitua, Hugo Alberto; Tito Rigau, Javier; Multiple response optimization of heat shock process for separation of bovine serum albumin from plasma; Taylor; Separation Science and Technology; 52; 12; 8-2017; 1992-2001
Compartir
Altmétricas