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dc.contributor.author
Saranz, R.J.
dc.contributor.author
Lozano, A.
dc.contributor.author
Lozano, N.A.
dc.contributor.author
Ponzio, Marina Flavia
dc.contributor.author
Cruz, Á. A.
dc.date.available
2018-11-07T17:49:39Z
dc.date.issued
2017-08-19
dc.identifier.citation
Saranz, R.J.; Lozano, A.; Lozano, N.A.; Ponzio, Marina Flavia; Cruz, Á. A.; Subclinical lower airways correlates of chronic allergic and non-allergic rhinitis; Wiley Blackwell Publishing, Inc; Clinical And Experimental Allergy; 47; 8; 19-8-2017; 988-997
dc.identifier.issn
0954-7894
dc.identifier.uri
http://hdl.handle.net/11336/63895
dc.description.abstract
The upper and lower airways behave as a physiological and pathophysiological unit. Subclinical lower airways abnormalities have been described in patients with rhinitis without asthma. These are expressed as bronchial hyperreactivity, abnormalities in lung function and bronchial inflammation, likely as a result of the same phenomenon with systemic inflammatory impact that reaches both the nose and the lungs, which for unknown reasons does not always have a full clinical expression. Patients with rhinitis are at increased risk of developing asthma; therefore, most authors suggest a careful clinical evaluation and monitoring of these patients, especially if symptoms related to inflammation in the lower airways are observed. Although current treatments, such as H1-antihistamines, intranasal steroids and allergen immunotherapy, are quite effective for the management of rhinitis, it is difficult to prove their capacity to prevent asthma among subjects with rhinitis. Evidence showing that the treatment of rhinitis has a favourable impact on indicators of bronchial hyperreactivity and inflammation among subjects that have no symptoms of asthma is more frequently described. In this review, we address the frequency and characteristics of lower airway abnormalities in subjects with rhinitis, both in paediatric and adult populations, their likely predictive value for the development of asthma and the possibilities for therapeutic intervention that could modify the risk of subjects with rhinitis towards presenting asthma.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Wiley Blackwell Publishing, Inc
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Allergic Rinitis
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Spirometry
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Feno
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Non-Allergic Rhinitis
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Medicina Critica y de Emergencia
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Medicina Clínica
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CIENCIAS MÉDICAS Y DE LA SALUD
dc.title
Subclinical lower airways correlates of chronic allergic and non-allergic rhinitis
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2018-10-22T18:18:24Z
dc.journal.volume
47
dc.journal.number
8
dc.journal.pagination
988-997
dc.journal.pais
Reino Unido
dc.journal.ciudad
Londres
dc.description.fil
Fil: Saranz, R.J.. Universidad Católica de Córdoba. Facultad de Medicina. Clínica Universitaria Reina Fabiola; Argentina
dc.description.fil
Fil: Lozano, A.. Universidad Católica de Córdoba. Facultad de Medicina. Clínica Universitaria Reina Fabiola; Argentina
dc.description.fil
Fil: Lozano, N.A.. Universidad Católica de Córdoba. Facultad de Medicina. Clínica Universitaria Reina Fabiola; Argentina
dc.description.fil
Fil: Ponzio, Marina Flavia. Universidad Nacional de Córdoba;Facultad de Ciencias Médicas;Cátedra de Bioquímica Molecular; ; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina
dc.description.fil
Fil: Cruz, Á. A.. Universidade Federal da Bahia; Brasil
dc.journal.title
Clinical And Experimental Allergy
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/https://dx.doi.org/10.1111/cea.12938
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/abs/10.1111/cea.12938
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