Artículo
Cascade cyclization triggered by imine formation. Formal synthesis of the alkaloid (±)-stemoamide and its 9a-epimer
Fecha de publicación:
10/2015
Editorial:
Elsevier
Revista:
Tetrahedron Letters
ISSN:
0040-4039
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
A concise formal synthesis of stemoamide ( 1) and its 9a-epimer 14in 5 steps is described featuring a cas-cade cyclization triggered by imine formation. A good selectivity for either epimer is readily accom-plished by variation of the ester ( 9bor 9a, respectively) and the reaction conditions.
Palabras clave:
Cascade Cyclization
,
Imine
,
Formal Synthesis
,
Stemoamide
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Identificadores
Colecciones
Articulos(IQUIR)
Articulos de INST.DE QUIMICA ROSARIO
Articulos de INST.DE QUIMICA ROSARIO
Citación
Brito, Gilmar A.; Sarotti, Ariel Marcelo; Wipf, Peter; Pilli, Ronaldo A.; Cascade cyclization triggered by imine formation. Formal synthesis of the alkaloid (±)-stemoamide and its 9a-epimer; Elsevier; Tetrahedron Letters; 56; 48; 10-2015; 6664-6668
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