Mostrar el registro sencillo del ítem

dc.contributor.author
Rodriguez Granillo, Gaston Alfredo  
dc.contributor.author
Carrascosa, Patricia  
dc.contributor.author
Deviggiano, Alejandro  
dc.contributor.author
Capunay, Carlos  
dc.contributor.author
De Zan, Macarena C.  
dc.contributor.author
Goldsmit, Alejandro  
dc.contributor.author
Campisi, Roxana  
dc.date.available
2018-09-13T19:48:48Z  
dc.date.issued
2017-07  
dc.identifier.citation
Rodriguez Granillo, Gaston Alfredo; Carrascosa, Patricia; Deviggiano, Alejandro; Capunay, Carlos; De Zan, Macarena C.; et al.; Pericardial fat volume is related to atherosclerotic plaque burden rather than to lesion severity; Oxford University Press; European Heart Journal. Cardiovascular Imaging; 18; 7; 7-2017; 795-801  
dc.identifier.issn
2047-2404  
dc.identifier.uri
http://hdl.handle.net/11336/59620  
dc.description.abstract
Aims: We sought to explore the relationship between pericardial fat volume (PFV) and both coronary atherosclerosis (CA) extent and severity using coronary artery calcium score (CAC), computed tomography coronary angiography (CTCA), and invasive coronary angiography in patients at high to intermediate likelihood of coronary artery disease (CAD). Methods and results: Patients clinically referred to invasive angiography who underwent CTCA and CAC within 1 month before the procedure comprised the study population. PFV, CAC, atherosclerotic burden indexes [segment involvement score (SIS); segment stenosis score; three-vessel plaque; and any left main plaque], and the invasive angiography-derived CAD index were evaluated independently. A total of 75 patients were included in the study. PFV did not differ between patients with or without obstructive (stenosis .70%) CAD defined by invasive angiography (86.4±31.7 vs. 77.1±42.8 cm3, P = 0.34), although patients with obstructive CAD had significantly higher CAC scores [636.0 (IQR 229.5-1101.0) vs. 206.0 (IQR 0.0-675), P<0.0001] than patients without obstructive CAD. Patients with extensive CA (SIS . 5) had significantly larger PFV (89.9±33.9 vs. 58.7±33.2 cm3, P = 0.003) than patients with non-extensive CA. Significant correlations were found between PFV and CAC (r = 0.49, P<0.0001), and SIS (r = 0.46, P<0.0001), whereas very weak correlations were observed between PFV and the CAD index (r = 0.27, P = 0.02), and between PFV and the body mass index (r = 0.33, P = 0.004). Conclusion: The main finding of the present study was the identification of PFV as more closely related to atherosclerotic plaque burden rather than to lesion severity in patients referred to invasive coronary angiography.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Oxford University Press  
dc.rights
info:eu-repo/semantics/openAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
Adipose Tissue  
dc.subject
Angiography  
dc.subject
Atherosclerosis  
dc.subject
Calcium  
dc.subject
Computed Tomography  
dc.subject
Stenosis  
dc.subject.classification
Medicina Critica y de Emergencia  
dc.subject.classification
Medicina Clínica  
dc.subject.classification
CIENCIAS MÉDICAS Y DE LA SALUD  
dc.title
Pericardial fat volume is related to atherosclerotic plaque burden rather than to lesion severity  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2018-09-11T14:48:20Z  
dc.identifier.eissn
2047-2412  
dc.journal.volume
18  
dc.journal.number
7  
dc.journal.pagination
795-801  
dc.journal.pais
Reino Unido  
dc.journal.ciudad
Oxford  
dc.description.fil
Fil: Rodriguez Granillo, Gaston Alfredo. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Cardiológicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Cardiológicas; Argentina. Diagnóstico Maipú; Argentina  
dc.description.fil
Fil: Carrascosa, Patricia. Diagnóstico Maipú; Argentina  
dc.description.fil
Fil: Deviggiano, Alejandro. Diagnóstico Maipú; Argentina  
dc.description.fil
Fil: Capunay, Carlos. Diagnóstico Maipú; Argentina  
dc.description.fil
Fil: De Zan, Macarena C.. Diagnóstico Maipú; Argentina  
dc.description.fil
Fil: Goldsmit, Alejandro. Sanatorio Güemes; Argentina  
dc.description.fil
Fil: Campisi, Roxana. Diagnóstico Maipú; Argentina  
dc.journal.title
European Heart Journal. Cardiovascular Imaging  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://academic.oup.com/ehjcimaging/article/18/7/795/3060605  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1093/ehjci/jew139