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dc.contributor.author
Peichoto, María Elisa  
dc.contributor.author
Paes Leme, Adriana F.  
dc.contributor.author
Pauletti, Bianca A.  
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Correia Batista, Isabel  
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Mackessy, Stephen P.  
dc.contributor.author
Acosta, Ofelia Cristina  
dc.contributor.author
Santoro, Marcelo Larami  
dc.date.available
2018-09-06T21:45:12Z  
dc.date.issued
2010-09  
dc.identifier.citation
Peichoto, María Elisa; Paes Leme, Adriana F.; Pauletti, Bianca A.; Correia Batista, Isabel; Mackessy, Stephen P.; et al.; Autolysis at the disintegrin domain of patagonfibrase, a metalloproteinase from Philodryas patagoniensis (Patagonia Green Racer; Dipsadidae) venom; Elsevier Science; Biochimica Et Biophysica Acta-proteins And Proteomics; 1804; 9; 9-2010; 1937-1942  
dc.identifier.issn
1570-9639  
dc.identifier.uri
http://hdl.handle.net/11336/58642  
dc.description.abstract
Patago-calcium markedly enhanced the azocaseinolytic activity of patagonfibrase. Our findings contribute to the understanding of the structural and mechanistic bases of this family of metalloenzymes that are widely distributed among snake venoms, demonstrating that important post-translational modifications such as proteolysis can also contribute to the diversity and complexity of proteins found in rear-fanged snake venoms.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Elsevier Science  
dc.rights
info:eu-repo/semantics/openAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
Autodegradation  
dc.subject
Colubridae  
dc.subject
Metalloproteinase  
dc.subject.classification
Química Orgánica  
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Ciencias Químicas  
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CIENCIAS NATURALES Y EXACTAS  
dc.title
Autolysis at the disintegrin domain of patagonfibrase, a metalloproteinase from Philodryas patagoniensis (Patagonia Green Racer; Dipsadidae) venom  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2018-08-30T14:37:01Z  
dc.journal.volume
1804  
dc.journal.number
9  
dc.journal.pagination
1937-1942  
dc.journal.pais
Países Bajos  
dc.journal.ciudad
Amsterdam  
dc.description.fil
Fil: Peichoto, María Elisa. Universidad Nacional del Nordeste. Facultad de Ciencias Veterinarias; Argentina. Instituto Butantan. Laboratório de Fisiopatologia; Brasil. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Nordeste; Argentina  
dc.description.fil
Fil: Paes Leme, Adriana F.. Centro Nacional de Pesquisa Em Energia E Materiais; Brasil  
dc.description.fil
Fil: Pauletti, Bianca A.. Centro Nacional de Pesquisa Em Energia E Materiais; Brasil  
dc.description.fil
Fil: Correia Batista, Isabel. Instituto Butantan. Laboratório de Bioquímica e Biofísica; Brasil  
dc.description.fil
Fil: Mackessy, Stephen P.. University of Northern Colorado; Estados Unidos  
dc.description.fil
Fil: Acosta, Ofelia Cristina. Universidad Nacional del Nordeste. Facultad de Cs.veterinarias. Departamento de Clinica. Cátedra de Farmacología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Nordeste; Argentina  
dc.description.fil
Fil: Santoro, Marcelo Larami. Instituto Butantan. Laboratório de Fisiopatologia; Brasil  
dc.journal.title
Biochimica Et Biophysica Acta-proteins And Proteomics  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/https://doi.org/10.1016/j.bbapap.2010.06.005  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S1570963910001639